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ABCA8 blocking peptide

Scan QR to view Datasheet Catalog #    MBS822803 ABCA8 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCA8, Blocking Peptide

 Also Known As   

ABCA8 Blocking Peptide

 Product Synonym Names    KIAA0822; ATP-binding cassette sub-family A member 8
 Product Gene Name   

ABCA8 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    ABCA8 peptide (MBS822803) is used for blocking the activity of ABCA8 antibody (MBS821789)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612505
 3D Structure    ModBase 3D Structure for O94911
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 Host    Synthetic
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >85%
 Form/Format    Lyophilized powder
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 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of ABCA8 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ABCA8 blocking peptide

   The peptide is used to block Anti-ABCA8 Antibody reactivity.
 Applications Tested/Suitable for ABCA8 blocking peptide   

Blocking (BL)

 Application Notes for ABCA8 blocking peptide    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for ABCA8. It may not necessarily be applicable to this product.
 NCBI GI #    572882597
 NCBI GeneID    10351
 NCBI Accession #    NP_001275914.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001288985.1 [Other Products]
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 UniProt Primary Accession #    O94911 [Other Products]
 UniProt Secondary Accession #    Q86WW0; A1L3U3; C9JQE6 [Other Products]
 UniProt Related Accession #    O94911 [Other Products]
 Molecular Weight    183,677 Da
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 NCBI Official Full Name    ATP-binding cassette sub-family A member 8 isoform 1
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family A (ABC1), member 8
 NCBI Official Symbol    ABCA8 [Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family A member 8
 UniProt Protein Name    ATP-binding cassette sub-family A member 8
 Protein Family    ABC transporter A family
 UniProt Gene Name    ABCA8 [Similar Products]
 UniProt Synonym Gene Names    KIAA0822 [Similar Products]
 UniProt Entry Name    ABCA8_HUMAN
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 NCBI Summary for ABCA8    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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 UniProt Comments for ABCA8    ABCA8: ATP-dependent lipophilic drug transporter. Belongs to the ABC transporter superfamily. ABCA family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family; Mitochondrial; Transporter

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: mitochondrial inner membrane; plasma membrane; integral to membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: metabolic process; transport; transmembrane transport
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 Research Articles on ABCA8    1. These data suggest a direct relationship between the levels of ABCA8 and the ectopic expression of alpha-syn and increased expression of p25alpha
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ABCA8 blocking peptidePathways associated with ABCA8 blocking peptide
 Reference Product  PubMed Publications
 ABCA6 blocking peptide  >6 publications with ABCA8 and ABCA6
 ABCC2 blocking peptide  >2 publications with ABCA8 and ABCC2
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with ABCA8 blocking peptideOrgans/Tissues associated with ABCA8 blocking peptide
 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >3 publications with ABCA8 and Ovarian Neoplasms
 Brain Diseases Antibodies  >2 publications with ABCA8 and Brain Diseases
 Nervous System Diseases Antibodies  >2 publications with ABCA8 and Nervous System Diseases
 Inflammation Antibodies  >1 publications with ABCA8 and Inflammation
 Colorectal Neoplasms Antibodies  >1 publications with ABCA8 and Colorectal Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with ABCA8 and Brain
 Heart Antibodies  >5 publications with ABCA8 and Heart
 Liver Antibodies  >5 publications with ABCA8 and Liver
 Nerve Antibodies  >3 publications with ABCA8 and Nerve
 Lung Antibodies  >2 publications with ABCA8 and Lung
 Vascular Antibodies  >2 publications with ABCA8 and Vascular
 Muscle Antibodies  >2 publications with ABCA8 and Muscle
 Pancreas Antibodies  >1 publications with ABCA8 and Pancreas
 Testis Antibodies  >1 publications with ABCA8 and Testis
 Kidney Antibodies  >1 publications with ABCA8 and Kidney
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