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ABCG1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS823933 ABCG1 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCG1, Blocking Peptide

 Also Known As   

ABCG1 Blocking Peptide

 Product Synonym Names    ABC8; WHT1; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog
 Product Gene Name   

ABCG1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    ABCG1 peptide (MBS823933) is used for blocking the activity of ABCG1 antibody (MBS820666)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603076
 3D Structure    ModBase 3D Structure for P45844
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 Host    Synthetic
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >85%
 Form/Format    Lyophilized powder
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 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of ABCG1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ABCG1 blocking peptide

   The peptide is used to block Anti-ABCG1 Antibody reactivity.
 Applications Tested/Suitable for ABCG1 blocking peptide   

Blocking (BL)

 Application Notes for ABCG1 blocking peptide    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for ABCG1. It may not necessarily be applicable to this product.
 NCBI GI #    46592915
 NCBI GeneID    9619
 NCBI Accession #    NP_004906.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_004915.3 [Other Products]
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 UniProt Primary Accession #    P45844 [Other Products]
 UniProt Secondary Accession #    Q86SU8; Q96L76; Q9BXK6; Q9BXK7; Q9BXK8; Q9BXK9; Q9BXL0; Q9BXL1; Q9BXL2; Q9BXL3; Q9BXL4 [Other Products]
 UniProt Related Accession #    P45844 [Other Products]
 Molecular Weight    86,628 Da
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 NCBI Official Full Name    ATP-binding cassette sub-family G member 1 isoform 4
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family G (WHITE), member 1
 NCBI Official Symbol    ABCG1 [Similar Products]
 NCBI Official Synonym Symbols   
ABC8; WHITE1
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family G member 1; ABC transporter 8; homolog of Drosophila white; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; white protein homolog (ATP-binding cassette transporter 8)
 UniProt Protein Name    ATP-binding cassette sub-family G member 1
 UniProt Synonym Protein Names   
ATP-binding cassette transporter 8; White protein homolog
 Protein Family    ABC transporter G family
 UniProt Gene Name    ABCG1 [Similar Products]
 UniProt Synonym Gene Names    ABC8; WHT1 [Similar Products]
 UniProt Entry Name    ABCG1_HUMAN
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 NCBI Summary for ABCG1    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCG1    ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family; Transporter

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: Golgi membrane; nucleoplasm; Golgi apparatus; recycling endosome; endoplasmic reticulum membrane; mitochondrion; intracellular membrane-bound organelle; integral to plasma membrane; plasma membrane; endosome; external side of plasma membrane

Molecular Function: protein dimerization activity; protein binding; protein homodimerization activity; phospholipid transporter activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; toxin transporter activity; sterol-transporting ATPase activity; phospholipid binding; ADP binding; ATP binding

Biological Process: response to organic substance; cholesterol metabolic process; cholesterol homeostasis; amyloid precursor protein catabolic process; reverse cholesterol transport; detection of hormone stimulus; response to high density lipoprotein stimulus; regulation of transcription, DNA-dependent; phospholipid efflux; positive regulation of cholesterol biosynthetic process; cholesterol efflux; intracellular cholesterol transport; lipoprotein metabolic process; response to lipid; transmembrane transport; phospholipid homeostasis
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 Research Articles on ABCG1    1. I human macrophages, polyunsaturated fatty acids such as EPA have an effect on the cholesterol homeostasis in macrophages, and they can change the expression of ABCG1 gene.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCG1 blocking peptideDiseases associated with ABCG1 blocking peptide
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Nuclear Receptors In Lipid Metabolism And Toxicity Pathway antibodies  Nuclear Receptors In Lipid Metabolism And Toxicity Pathway Diagram
 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >292 publications with ABCG1 and Atherosclerosis
 Cardiovascular Diseases Antibodies  >197 publications with ABCG1 and Cardiovascular Diseases
 Inflammation Antibodies  >98 publications with ABCG1 and Inflammation
 Dyslipidemias Antibodies  >54 publications with ABCG1 and Dyslipidemias
 Liver Diseases Antibodies  >51 publications with ABCG1 and Liver Diseases
 Fatty Liver Antibodies  >47 publications with ABCG1 and Fatty Liver
 Hyperlipidemias Antibodies  >35 publications with ABCG1 and Hyperlipidemias
 Hypercholesterolemia Antibodies  >32 publications with ABCG1 and Hypercholesterolemia
 Necrosis Antibodies  >30 publications with ABCG1 and Necrosis
 Nervous System Diseases Antibodies  >27 publications with ABCG1 and Nervous System Diseases
Organs/Tissues associated with ABCG1 blocking peptide
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >315 publications with ABCG1 and Liver
 Blood Antibodies  >203 publications with ABCG1 and Blood
 Brain Antibodies  >53 publications with ABCG1 and Brain
 Muscle Antibodies  >36 publications with ABCG1 and Muscle
 Lung Antibodies  >36 publications with ABCG1 and Lung
 Intestine Antibodies  >22 publications with ABCG1 and Intestine
 Kidney Antibodies  >22 publications with ABCG1 and Kidney
 Connective Tissue Antibodies  >12 publications with ABCG1 and Connective Tissue
 Spleen Antibodies  >12 publications with ABCG1 and Spleen
 Pancreas Antibodies  >11 publications with ABCG1 and Pancreas
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