Q15041.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,158 Da
NCBI Official Full Name
ADP-ribosylation factor-like protein 6-interacting protein 1
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 6 interacting protein 1
NCBI Protein Information
ADP-ribosylation factor-like protein 6-interacting protein 1; aip-1; ARL-6-interacting protein 1; apoptotic regulator in the membrane of the endoplasmic reticulum
UniProt Protein Name
ADP-ribosylation factor-like protein 6-interacting protein 1
UniProt Synonym Gene Names
UniProt Entry Name
AR6P1_HUMAN
NCBI Summary for ARL6IP1
This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
UniProt Comments for ARL6IP1
ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 16p12-p11.2
Cellular Component: membrane; integral to membrane; translocon complex; cytosol
Molecular Function: protein binding
Biological Process: cotranslational protein targeting to membrane
Disease: Spastic Paraplegia 61, Autosomal Recessive
Research Articles on ARL6IP1
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Products associated with ARL6IP1 blocking peptide
Diseases associated with ARL6IP1 blocking peptide
Organs/Tissues associated with ARL6IP1 blocking peptide
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