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ATF7 blocking peptide

Scan QR to view Datasheet Catalog #    MBS9227882 ATF7 blocking peptide
Unit / Price
0.1 mg  /  $155 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATF7, Blocking Peptide

 Also Known As   

ATF7 Antibody (N-term) Blocking Peptide

 Product Synonym Names    Cyclic AMP-dependent transcription factor ATF-7; cAMP-dependent transcription factor ATF-7; Activating transcription factor 7; Transcription factor ATF-A; ATF7; ATFA
 Product Gene Name   

ATF7 blocking peptide

[Similar Products]
 Product Synonym Gene Name    ATFA [Similar Products]
 Antibody/Peptide Pairs    ATF7 peptide (MBS9227882) is used for blocking the activity of ATF7 antibody (MBS9212522)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606371
 3D Structure    ModBase 3D Structure for P17544
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 Specificity    The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human ATF7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
 Form/Format    Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
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 Cellular Location    Nucleus. Nucleus, nucleoplasm. Note: Mainly nucleoplasmic. Restricted distribution to the perinuculear region The sumoylated form locates to the nuclear periphery
 Tissue Location    Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta.
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
 Other Notes    Small volumes of ATF7 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ATF7 blocking peptide

   Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]- 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
NCBI/Uniprot data below describe general gene information for ATF7. It may not necessarily be applicable to this product.
 NCBI GI #    12643393
 NCBI GeneID    11016
 NCBI Accession #    P17544.2 [Other Products]
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 UniProt Primary Accession #    P17544 [Other Products]
 UniProt Secondary Accession #    Q13814; Q8IVR8; Q9UD83; A5D6Y4; B2RMP1; B4DQL4 [Other Products]
 UniProt Related Accession #    P17544 [Other Products]
 Molecular Weight    51,757 Da
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 NCBI Official Full Name    Cyclic AMP-dependent transcription factor ATF-7
 NCBI Official Synonym Full Names    activating transcription factor 7
 NCBI Official Symbol    ATF7 [Similar Products]
 NCBI Official Synonym Symbols   
ATFA
[Similar Products]
 NCBI Protein Information    cyclic AMP-dependent transcription factor ATF-7
 UniProt Protein Name    Cyclic AMP-dependent transcription factor ATF-7
 UniProt Synonym Protein Names   
Activating transcription factor 7; Transcription factor ATF-A
 Protein Family    Cyclic AMP-dependent transcription factor
 UniProt Gene Name    ATF7 [Similar Products]
 UniProt Synonym Gene Names    ATFA; cAMP-dependent transcription factor ATF-7 [Similar Products]
 UniProt Entry Name    ATF7_HUMAN
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 UniProt Comments for ATF7    Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
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 Research Articles on ATF7    1. mitotic stabilized ATF7 protein re-localizes onto chromatin at the end of telophase and contributes to induce the cyclin D1 gene expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ATF7 blocking peptidePathways associated with ATF7 blocking peptide
 Reference Product  PubMed Publications
 TAF12 blocking peptide  >5 publications with ATF7 and TAF12
 FOS blocking peptide  >4 publications with ATF7 and FOS
 PTP4A1 blocking peptide  >1 publications with ATF7 and PTP4A1
 MAPK8 blocking peptide  >1 publications with ATF7 and MAPK8
 Products by Pathway  Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
Diseases associated with ATF7 blocking peptideOrgans/Tissues associated with ATF7 blocking peptide
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >4 publications with ATF7 and Necrosis
 Cell Transformation, Neoplastic Antibodies  >2 publications with ATF7 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with ATF7 and Neoplasm Metastasis
 Brain Diseases Antibodies  >1 publications with ATF7 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with ATF7 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >3 publications with ATF7 and Bone Marrow
 Bone Antibodies  >3 publications with ATF7 and Bone
 Blood Antibodies  >3 publications with ATF7 and Blood
 Lung Antibodies  >1 publications with ATF7 and Lung
 Lymph Node Antibodies  >1 publications with ATF7 and Lymph Node
 Liver Antibodies  >1 publications with ATF7 and Liver
 Heart Antibodies  >1 publications with ATF7 and Heart
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