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BACH1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS822959 BACH1 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BACH1, Blocking Peptide

★Popular Item★
 Also Known As   

BACH1 Blocking Peptide

 Product Synonym Names    Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303
 Product Gene Name   

BACH1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    BACH1 peptide (MBS822959) is used for blocking the activity of BACH1 antibody (MBS822159)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602751
 3D Structure    ModBase 3D Structure for Q16696
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 Species Reactivity    Human, Monkey
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 Purity/Purification    >85%
 Form/Format    Lyophilized powder
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 Source    Synthetic
 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of BACH1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for BACH1 blocking peptide

   The peptide is used to block Anti-BACH1 Antibody reactivity.
 Applications Tested/Suitable for BACH1 blocking peptide   

Blocking (BL)

 Application Notes for BACH1 blocking peptide    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for BACH1. It may not necessarily be applicable to this product.
 NCBI GI #    4502353
 NCBI GeneID    571
 NCBI Accession #    NP_001177.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001186.3 [Other Products]
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 UniProt Primary Accession #    Q16696 [Other Products]
 UniProt Secondary Accession #    O43285; Q6ICU0 [Other Products]
 UniProt Related Accession #    O14867 [Other Products]
 Molecular Weight    81,958 Da
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 NCBI Official Full Name    transcription regulator protein BACH1
 NCBI Official Synonym Full Names    BTB and CNC homology 1, basic leucine zipper transcription factor 1
 NCBI Official Symbol    BACH1 [Similar Products]
 NCBI Official Synonym Symbols   
BACH-1; BTBD24
[Similar Products]
 NCBI Protein Information    transcription regulator protein BACH1; basic region leucine zipper transcriptional regulator BACH1
 UniProt Protein Name    Transcription regulator protein BACH1
 UniProt Synonym Protein Names   
BTB and CNC homolog 1; HA2303
 Protein Family    Transcription regulator protein
 UniProt Gene Name    BACH1 [Similar Products]
 UniProt Entry Name    BACH1_HUMAN
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 NCBI Summary for BACH1    This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]
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 UniProt Comments for BACH1    BACH1: a transcriptional regulator that acts as a repressor or activator. Binds, in-vitro, to NF-E2 binding sites on DNA. Plays an important role in coordinating transcription activation and repression by NF-E2. Belongs to the bZIP family, CNC subfamily.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus

Molecular Function: heme binding; transcription factor activity

Biological Process: G1/S-specific transcription in mitotic cell cycle; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; G2/M-specific transcription in mitotic cell cycle
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 Research Articles on BACH1    1. The Bach1-dependent repression of the HO-1 expression is under the control of the Hx-dependent uptake of extracellular heme
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BACH1 blocking peptidePathways associated with BACH1 blocking peptide
 Reference Product  PubMed Publications
 HMOX1 blocking peptide  >106 publications with BACH1 and HMOX1
 BRCA1 blocking peptide  >73 publications with BACH1 and BRCA1
 MAFK blocking peptide  >19 publications with BACH1 and MAFK
 MLH1 blocking peptide  >13 publications with BACH1 and MLH1
 BARD1 blocking peptide  >6 publications with BACH1 and BARD1
 MAFG blocking peptide  >5 publications with BACH1 and MAFG
 Products by Pathway  Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
Diseases associated with BACH1 blocking peptideOrgans/Tissues associated with BACH1 blocking peptide
 Disease Name  Pubmed Publications
 Anemia Antibodies  >168 publications with BACH1 and Anemia
 Nervous System Diseases Antibodies  >15 publications with BACH1 and Nervous System Diseases
 Inflammation Antibodies  >14 publications with BACH1 and Inflammation
 Congenital Abnormalities Antibodies  >12 publications with BACH1 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >11 publications with BACH1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >10 publications with BACH1 and Liver Diseases
 Immune System Diseases Antibodies  >8 publications with BACH1 and Immune System Diseases
 Neoplasms, Experimental Antibodies  >8 publications with BACH1 and Neoplasms, Experimental
 Heart Diseases Antibodies  >6 publications with BACH1 and Heart Diseases
 Necrosis Antibodies  >6 publications with BACH1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >25 publications with BACH1 and Blood
 Liver Antibodies  >24 publications with BACH1 and Liver
 Bone Antibodies  >17 publications with BACH1 and Bone
 Lung Antibodies  >11 publications with BACH1 and Lung
 Vascular Antibodies  >11 publications with BACH1 and Vascular
 Brain Antibodies  >9 publications with BACH1 and Brain
 Skin Antibodies  >7 publications with BACH1 and Skin
 Muscle Antibodies  >5 publications with BACH1 and Muscle
 Kidney Antibodies  >3 publications with BACH1 and Kidney
 Intestine Antibodies  >2 publications with BACH1 and Intestine
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