Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Blocking Peptide rightarrow BAG1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • FZD4 Antibody
 • Insulin Autoantibody (IAA) ELISA Kit
 • Serum -Glucocorticoid Inducible Protein Kinase (SGK) ELISA Kit
 • Galactose 6-Sulphate Sulphatase (GAL-6S) ELISA Kit
 • High Molecular Weight Adiponectin (HMW ADNP) ELISA Kit
 • Insulin Like Growth Factor Binding Protein 6 (IGFBP6) ELISA Kit
 • Dendritic Cell Associated C Type Lectin 1 (DCAL-2) ELISA Kit
 • Heparin Associated Antibody (PF4) ELISA Kit
 • Phospholamban (PLN) ELISA Kit
 • Apobec 1 Complementation Factor (A1CF) ELISA Kit
 • Plakophilin 2 (PKP2) ELISA Kit
 • Soluble Fms-Like Tyrosine 1 (SFLT1) ELISA Kit
 • Transforming Growth Factor Beta Induced (TGFBI) ELISA Kit
 • Retinoic Acid Inducible Gene-Rig-Like Receptor (RLR-9) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

BAG1 blocking peptide :: BAG-1 Blocking Peptide

Scan QR to view Datasheet Catalog #    MBS152922 BAG1 blocking peptide
Unit / Price
0.05 mg  /  $135 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BAG-1 (BAG1), Blocking Peptide

 Also Known As   

BAG-1 Peptide

 Product Synonym Names    HAP; BAG-1; RAP46; HAP; BAG family molecular chaperone regulator 1; Bcl-2-associated athanogene 1; BCL2-associated athanogene
 Product Gene Name   

BAG1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    BAG-1 peptide (MBS152922) is used for blocking the activity of BAG-1 antibody (MBS151129)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Western Blot Protocol    Western Blot Peptide Blocking Protocol
 OMIM    601497
 3D Structure    ModBase 3D Structure for Q99933
Section Bar
Section Bar
 Form/Format    Liquid
 Concentration    200 ug/mL (lot specific)
Section Bar
 Species    Human
 Buffer    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
 Location    14 amino acids near the carboxy terminus of human BAG1.
Section Bar
 Preparation and Storage    Store BAG-1 peptide at -20 degree C, stable for one year.
 Other Notes    Small volumes of BAG1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for BAG1 blocking peptide   

Blocking (BL)

 Application Notes for BAG1 blocking peptide    BAG-1 peptide is used for blocking the activity of BAG1 antibody.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for BAG1. It may not necessarily be applicable to this product.
 NCBI GI #    124494251
 NCBI GeneID    573
 NCBI Accession #    NP_004314 [Other Products]
 NCBI GenBank Nucleotide #    NM_004323.4 [Other Products]
Section Bar
 UniProt Primary Accession #    Q99933 [Other Products]
 UniProt Secondary Accession #    O75315; Q14414; Q53H32; Q5VZE8; Q5VZE9; Q5VZF0; Q96TG2; Q9Y2V4 [Other Products]
 UniProt Related Accession #    Q99933 [Other Products]
 Molecular Weight    25,989 Da
Table BarTOPTable Bar
 NCBI Official Full Name    BCL2-associated athanogene isoform 1L
 NCBI Official Synonym Full Names    BCL2-associated athanogene
 NCBI Official Symbol    BAG1 [Similar Products]
 NCBI Official Synonym Symbols   
HAP; BAG-1; RAP46
[Similar Products]
 NCBI Protein Information    BAG family molecular chaperone regulator 1; Bcl-2-binding protein; receptor-associated protein, 46-KD; Bcl-2 associating athanogene-1 protein; glucocortoid receptor-associated protein RAP46
 UniProt Protein Name    BAG family molecular chaperone regulator 1
 UniProt Synonym Protein Names   
Bcl-2-associated athanogene 1
 Protein Family    BAG family molecular chaperone regulator
 UniProt Gene Name    BAG1 [Similar Products]
 UniProt Synonym Gene Names    HAP; BAG-1 [Similar Products]
 UniProt Entry Name    BAG1_HUMAN
Section Bar
 NCBI Summary for BAG1    The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]
Section Bar
 UniProt Comments for BAG1    BAG1: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli. Homodimer. Forms a heteromeric complex with HSP70/HSC70. Binds to the ATPase domain of HSP/HSC70 chaperones. Isoform 1, isoform 3 and isoform 4 but not isoform 2 interact with HSPA8/HSC70. Interacts with NR3C1. Interacts with the N-terminal region of STK19. Interacts with PPP1R15A. Interacts with BCL2 in an ATP-dependent manner. Isoform 2 does not interact with BCL2. Up-regulated during differentiation of bladder epithelial cells and down-regulated during differentiation of prostate epithelium. Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tumor cell lines, and at consistently high levels in leukemia and lymphoma cell lines. Isoform 1 is expressed in the prostate, breast and leukemia cell lines. Isoform 3 is the least abundant isoform in tumor cell lines. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 9p12

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; chaperone binding; receptor signaling protein activity

Biological Process: cell surface receptor linked signal transduction; apoptosis; negative regulation of apoptosis
Table BarTOPTable Bar
 Research Articles on BAG1    1. distinct isoforms of BAG-1 had different anti-apoptotic ability in breast cancer cells treated with the 4-OH TAM.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with BAG1 blocking peptideDiseases associated with BAG1 blocking peptide
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >16 publications with BAG1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >10 publications with BAG1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >9 publications with BAG1 and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >4 publications with BAG1 and Cell Transformation, Neoplastic
 Adenocarcinoma Antibodies  >4 publications with BAG1 and Adenocarcinoma
 Nerve Degeneration Antibodies  >3 publications with BAG1 and Nerve Degeneration
 Prostatic Neoplasms Antibodies  >3 publications with BAG1 and Prostatic Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with BAG1 and Neoplasms, Experimental
 Heart Diseases Antibodies  >2 publications with BAG1 and Heart Diseases
 Inflammation Antibodies  >2 publications with BAG1 and Inflammation
Organs/Tissues associated with BAG1 blocking peptide
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >126 publications with BAG1 and Muscle
 Nerve Antibodies  >49 publications with BAG1 and Nerve
 Brain Antibodies  >43 publications with BAG1 and Brain
 Blood Antibodies  >25 publications with BAG1 and Blood
 Embryonic Tissue Antibodies  >14 publications with BAG1 and Embryonic Tissue
 Heart Antibodies  >9 publications with BAG1 and Heart
 Eye Antibodies  >8 publications with BAG1 and Eye
 Lung Antibodies  >6 publications with BAG1 and Lung
 Liver Antibodies  >5 publications with BAG1 and Liver
 Prostate Antibodies  >4 publications with BAG1 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions