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TNFRSF4 blocking peptide :: CD134 Blocking Peptide

Scan QR to view Datasheet Catalog #    MBS8204460 TNFRSF4 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD134 (TNFRSF4), Blocking Peptide

 Also Known As   

CD134 Blocking Peptide

 Product Synonym Names    TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD134
 Product Gene Name   

TNFRSF4 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    CD134 peptide (MBS8204460) is used for blocking the activity of CD134 antibody (MBS8232614)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600315
 3D Structure    ModBase 3D Structure for P43489
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 Host    Synthetic
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >85%
 Form/Format    Lyophilized powder
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 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
 Directions for Use    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of TNFRSF4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TNFRSF4 blocking peptide

   The peptide is used to block Anti-CD134 Antibody reactivity.
 Applications Tested/Suitable for TNFRSF4 blocking peptide   

Blocking (BL)

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NCBI/Uniprot data below describe general gene information for TNFRSF4. It may not necessarily be applicable to this product.
 NCBI GI #    4507579
 NCBI GeneID    7293
 NCBI Accession #    NP_003318.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003327.3 [Other Products]
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 UniProt Primary Accession #    P43489 [Other Products]
 UniProt Secondary Accession #    Q13663; Q2M312; Q5T7M0 [Other Products]
 UniProt Related Accession #    P43489 [Other Products]
 Molecular Weight    29,341 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 4
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 4
 NCBI Official Symbol    TNFRSF4 [Similar Products]
 NCBI Official Synonym Symbols   
OX40; ACT35; CD134; IMD16; TXGP1L
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 4
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 4
 UniProt Synonym Protein Names   
ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD_antigen: CD134
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF4 [Similar Products]
 UniProt Synonym Gene Names    TXGP1L [Similar Products]
 UniProt Entry Name    TNR4_HUMAN
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 NCBI Summary for TNFRSF4    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNFRSF4    TNFRSF4: Receptor for TNFSF4/OX40L/GP34.

Protein type: Membrane protein, integral; Apoptosis; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cell surface; integral to plasma membrane; external side of plasma membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: T cell proliferation; regulation of apoptosis; tumor necrosis factor-mediated signaling pathway; negative regulation of transcription factor activity; negative regulation of cytokine secretion; positive regulation of B cell proliferation; cellular defense response; immune response; positive regulation of immunoglobulin secretion; regulation of protein kinase activity; negative regulation of transcription, DNA-dependent; inflammatory response

Disease: Immunodeficiency 16
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 Research Articles on TNFRSF4    1. Data indicate that soluble OX40 and sOX40L plasma levels are increased in early rheumatoid arthritis patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFRSF4 blocking peptidePathways associated with TNFRSF4 blocking peptide
 Reference Product  PubMed Publications
 TNFSF4 blocking peptide  >195 publications with TNFRSF4 and TNFSF4
 TNFRSF9 blocking peptide  >41 publications with TNFRSF4 and TNFRSF9
 IL2RA blocking peptide  >18 publications with TNFRSF4 and IL2RA
 IL2RB blocking peptide  >4 publications with TNFRSF4 and IL2RB
 TSLP blocking peptide  >3 publications with TNFRSF4 and TSLP
 IL2RG blocking peptide  >3 publications with TNFRSF4 and IL2RG
 IL4 blocking peptide  >2 publications with TNFRSF4 and IL4
 TRAF1 blocking peptide  >2 publications with TNFRSF4 and TRAF1
 TRAF5 blocking peptide  >2 publications with TNFRSF4 and TRAF5
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 TNFR2 Non-canonical NF-kB Pathway antibodies  TNFR2 Non-canonical NF-kB Pathway Diagram
 TNFs Bind Their Physiological Receptors Pathway antibodies  TNFs Bind Their Physiological Receptors Pathway Diagram
Diseases associated with TNFRSF4 blocking peptideOrgans/Tissues associated with TNFRSF4 blocking peptide
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >297 publications with TNFRSF4 and Necrosis
 Immune System Diseases Antibodies  >127 publications with TNFRSF4 and Immune System Diseases
 Autoimmune Diseases Antibodies  >62 publications with TNFRSF4 and Autoimmune Diseases
 Disease Models, Animal Antibodies  >60 publications with TNFRSF4 and Disease Models, Animal
 Inflammation Antibodies  >51 publications with TNFRSF4 and Inflammation
 Hypersensitivity Antibodies  >26 publications with TNFRSF4 and Hypersensitivity
 Lung Diseases Antibodies  >24 publications with TNFRSF4 and Lung Diseases
 Nervous System Diseases Antibodies  >24 publications with TNFRSF4 and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >23 publications with TNFRSF4 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >22 publications with TNFRSF4 and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >354 publications with TNFRSF4 and Blood
 Lymph Node Antibodies  >48 publications with TNFRSF4 and Lymph Node
 Lung Antibodies  >24 publications with TNFRSF4 and Lung
 Skin Antibodies  >23 publications with TNFRSF4 and Skin
 Intestine Antibodies  >8 publications with TNFRSF4 and Intestine
 Kidney Antibodies  >6 publications with TNFRSF4 and Kidney
 Stomach Antibodies  >1 publications with TNFRSF4 and Stomach
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