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TNFRSF9 blocking peptide :: CD137 Blocking Peptide

Scan QR to view Datasheet Catalog #    MBS8243385 TNFRSF9 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD137 (TNFRSF9), Blocking Peptide

 Also Known As   

CD137 Blocking Peptide

 Product Synonym Names    CD137; ILA; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD137
 Product Gene Name   

TNFRSF9 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    CD137 peptide (MBS8243385) is used for blocking the activity of CD137 antibody (MBS8242890)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602250
 3D Structure    ModBase 3D Structure for Q07011
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 Species Reactivity    Human, Mouse, Monkey
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 Purity/Purification    >85%
 Form/Format    Lyophilized Powder
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 Source    Synthetic
    
 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of TNFRSF9 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for TNFRSF9 blocking peptide

   The peptide is used to block Anti-CD137 Antibody reactivity.
 Applications Tested/Suitable for TNFRSF9 blocking peptide   

Blocking (BL)

 Application Notes for TNFRSF9 blocking peptide    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for TNFRSF9. It may not necessarily be applicable to this product.
 NCBI GI #    728738
 NCBI GeneID    3604
 NCBI Accession #    Q07011.1 [Other Products]
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 UniProt Primary Accession #    Q07011 [Other Products]
 UniProt Secondary Accession #    P20334 [Other Products]
 UniProt Related Accession #    Q07011; AAB34924 [Other Products]
 Molecular Weight    27,899 Da
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 NCBI Official Full Name    Tumor necrosis factor receptor superfamily member 9
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily member 9
 NCBI Official Symbol    TNFRSF9 [Similar Products]
 NCBI Official Synonym Symbols   
ILA; 4-1BB; CD137; CDw137
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 9
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 9
 UniProt Synonym Protein Names   
4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD_antigen: CD137
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF9 [Similar Products]
 UniProt Synonym Gene Names    CD137; ILA [Similar Products]
 UniProt Entry Name    TNR9_HUMAN
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 NCBI Summary for TNFRSF9    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNFRSF9    TNFRSF9: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: external side of plasma membrane; extracellular space; integral to plasma membrane

Molecular Function: cytokine binding; receptor activity; tumor necrosis factor receptor activity

Biological Process: apoptosis; immune response; induction of apoptosis via death domain receptors; inflammatory response; multicellular organismal development; negative regulation of cell proliferation; regulation of apoptosis; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway
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 Research Articles on TNFRSF9    1. Our findings provide a novel, TNFRSF9-positive, reactive astrocytic phenotype in human gliomas
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFRSF9 blocking peptidePathways associated with TNFRSF9 blocking peptide
 Reference Product  PubMed Publications
 TNFSF9 blocking peptide  >78 publications with TNFRSF9 and TNFSF9
 TNFRSF4 blocking peptide  >43 publications with TNFRSF9 and TNFRSF4
 FAS blocking peptide  >23 publications with TNFRSF9 and FAS
 TRAF2 blocking peptide  >16 publications with TNFRSF9 and TRAF2
 IL2 blocking peptide  >7 publications with TNFRSF9 and IL2
 IL2RA blocking peptide  >3 publications with TNFRSF9 and IL2RA
 IL2RG blocking peptide  >2 publications with TNFRSF9 and IL2RG
 LRR1 blocking peptide  >1 publications with TNFRSF9 and LRR1
 MAP3K5 blocking peptide  >1 publications with TNFRSF9 and MAP3K5
 IL2RB blocking peptide  >1 publications with TNFRSF9 and IL2RB
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram
Diseases associated with TNFRSF9 blocking peptideOrgans/Tissues associated with TNFRSF9 blocking peptide
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >345 publications with TNFRSF9 and Necrosis
 Disease Models, Animal Antibodies  >110 publications with TNFRSF9 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >76 publications with TNFRSF9 and Neoplasms, Experimental
 Inflammation Antibodies  >58 publications with TNFRSF9 and Inflammation
 Lung Diseases Antibodies  >31 publications with TNFRSF9 and Lung Diseases
 Cardiovascular Diseases Antibodies  >25 publications with TNFRSF9 and Cardiovascular Diseases
 Liver Diseases Antibodies  >20 publications with TNFRSF9 and Liver Diseases
 Lung Neoplasms Antibodies  >19 publications with TNFRSF9 and Lung Neoplasms
 Liver Neoplasms Antibodies  >15 publications with TNFRSF9 and Liver Neoplasms
 Atherosclerosis Antibodies  >14 publications with TNFRSF9 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >7 publications with TNFRSF9 and Adipose Tissue
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