P11912.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,786 Da
NCBI Official Full Name
B-cell antigen receptor complex-associated protein alpha chain
NCBI Official Synonym Full Names
CD79a molecule
NCBI Official Synonym Symbols
NCBI Protein Information
B-cell antigen receptor complex-associated protein alpha chain
UniProt Protein Name
B-cell antigen receptor complex-associated protein alpha chain
UniProt Synonym Protein Names
Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD_antigen: CD79a
UniProt Synonym Gene Names
UniProt Entry Name
CD79A_HUMAN
NCBI Summary for CD79A
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for CD79A
Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: B cell receptor complex; cytoplasm; external side of plasma membrane; integral to plasma membrane; lipid raft; multivesicular body; plasma membrane
Molecular Function: protein binding
Biological Process: B cell activation; B cell differentiation; B cell proliferation; B cell receptor signaling pathway
Disease: Agammaglobulinemia 3, Autosomal Recessive
Research Articles on CD79A
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Products associated with CD79A blocking peptide
Pathways associated with CD79A blocking peptide
Diseases associated with CD79A blocking peptide
Organs/Tissues associated with CD79A blocking peptide
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