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CRYBA1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS9219074 CRYBA1 blocking peptide
Unit / Price
0.1 mg  /  $155 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRYBA1, Blocking Peptide

 Also Known As   

CRYBA1 Antibody (Center) Blocking peptide

 Product Synonym Names    Beta-crystallin A3; Beta-crystallin A3; isoform A1; Delta4 form; Beta-crystallin A3; isoform A1; Delta7 form; Beta-crystallin A3; isoform A1; Delta8 form; CRYBA1; CRYB1
 Product Gene Name   

CRYBA1 blocking peptide

[Similar Products]
 Product Synonym Gene Name    CRYB1 [Similar Products]
 Antibody/Peptide Pairs    CRYBA1 peptide (MBS9219074) is used for blocking the activity of CRYBA1 antibody (MBS9203274)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123610
 3D Structure    ModBase 3D Structure for P05813
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 Form/Format    Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
 Other Notes    Small volumes of CRYBA1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CRYBA1 blocking peptide

   Crystallins are the dominant structural components of the vertebrate eye lens.
NCBI/Uniprot data below describe general gene information for CRYBA1. It may not necessarily be applicable to this product.
 NCBI GI #    2506317
 NCBI GeneID    1411
 NCBI Accession #    P05813.4 [Other Products]
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 UniProt Primary Accession #    P05813 [Other Products]
 UniProt Secondary Accession #    Q13633; Q14CM9 [Other Products]
 UniProt Related Accession #    P05813 [Other Products]
 Molecular Weight    23,191 Da
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 NCBI Official Full Name    Beta-crystallin A3
 NCBI Official Synonym Full Names    crystallin beta A1
 NCBI Official Symbol    CRYBA1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    beta-crystallin A3
 UniProt Protein Name    Beta-crystallin A3
 Protein Family    Beta-crystallin
 UniProt Gene Name    CRYBA1 [Similar Products]
 UniProt Synonym Gene Names    CRYB1 [Similar Products]
 UniProt Entry Name    CRBA1_HUMAN
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 NCBI Summary for CRYBA1    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CRYBA1    CRYBA1: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital zonular cataract with sutural opacities. Two splice-variant isoforms have been described.

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: visual perception

Disease: Cataract 10, Multiple Types
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 Research Articles on CRYBA1    1. The findings suggest that impaired endolysosomal signaling in ocular astrocytes can cause PFV disease, by adversely affecting the vascular remodeling processes essential to ocular development, including regression of the fetal vasculature. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with CRYBA1 blocking peptideOrgans/Tissues associated with CRYBA1 blocking peptide
 Disease Name  Pubmed Publications
 Cataract, Congenital Zonular, with Sutural Opacities Antibodies  >2 publications with CRYBA1 and Cataract, Congenital Zonular, with Sutural Opacities
 Nervous System Diseases Antibodies  >1 publications with CRYBA1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >1 publications with CRYBA1 and Cardiovascular Diseases
 Hypertension Antibodies  >1 publications with CRYBA1 and Hypertension
 Carcinoma Antibodies  >1 publications with CRYBA1 and Carcinoma
 Infertility, Male Antibodies  >1 publications with CRYBA1 and Infertility, Male
 Nerve Degeneration Antibodies  >1 publications with CRYBA1 and Nerve Degeneration
 Weight Loss Antibodies  >1 publications with CRYBA1 and Weight Loss
 Inflammation Antibodies  >1 publications with CRYBA1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >55 publications with CRYBA1 and Eye
 Skin Antibodies  >2 publications with CRYBA1 and Skin
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