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DBP blocking peptide

Scan QR to view Datasheet Catalog #    MBS9229885 DBP blocking peptide
Unit / Price
0.1 mg  /  $155 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DBP, Blocking Peptide

 Also Known As   

DBP Blocking Peptide (C-term)

 Product Synonym Names    D site-binding protein; Albumin D box-binding protein; Albumin D-element-binding protein; Tax-responsive enhancer element-binding protein 302; TaxREB302; DBP
 Product Gene Name   

DBP blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    DBP peptide (MBS9229885) is used for blocking the activity of DBP antibody (MBS9207545)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    124097
 3D Structure    ModBase 3D Structure for Q10586
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 Specificity    The synthetic peptide sequence is selected from aa 233-246 of HUMAN DBP
 Form/Format    Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
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 Cellular Location    Nucleus.
 Tissue Location    Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
 Other Notes    Small volumes of DBP blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for DBP blocking peptide

   This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.
NCBI/Uniprot data below describe general gene information for DBP. It may not necessarily be applicable to this product.
 NCBI GI #    1706312
 NCBI GeneID    1628
 NCBI Accession #    Q10586.1 [Other Products]
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 UniProt Primary Accession #    Q10586 [Other Products]
 UniProt Secondary Accession #    A2I2P4 [Other Products]
 UniProt Related Accession #    Q10586 [Other Products]
 Molecular Weight    34,349 Da
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 NCBI Official Full Name    D site-binding protein
 NCBI Official Synonym Full Names    D-box binding PAR bZIP transcription factor
 NCBI Official Symbol    DBP [Similar Products]
 NCBI Official Synonym Symbols   
DABP
[Similar Products]
 NCBI Protein Information    D site-binding protein
 UniProt Protein Name    D site-binding protein
 UniProt Synonym Protein Names   
Albumin D box-binding protein; Albumin D-element-binding protein; Tax-responsive enhancer element-binding protein 302; TaxREB302
 Protein Family    D site-binding protein
 UniProt Gene Name    DBP [Similar Products]
 UniProt Synonym Gene Names    TaxREB302 [Similar Products]
 UniProt Entry Name    DBP_HUMAN
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 NCBI Summary for DBP    The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
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 UniProt Comments for DBP    DBP: This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. Belongs to the bZIP family. PAR subfamily.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 19q13.3

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
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 Research Articles on DBP    1. The interaction between vitamin D status, as measured by circulating 25(OH)D and DBP rs2282679 genotypes, modified the association between 25(OH)D and BMD and bone markers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DBP blocking peptidePathways associated with DBP blocking peptide
 Reference Product  PubMed Publications
 CLOCK blocking peptide  >222 publications with DBP and CLOCK
 ARNTL blocking peptide  >78 publications with DBP and ARNTL
 HLF blocking peptide  >35 publications with DBP and HLF
 NPAS2 blocking peptide  >17 publications with DBP and NPAS2
 CEBPA blocking peptide  >7 publications with DBP and CEBPA
 PDXK blocking peptide  >1 publications with DBP and PDXK
 Products by Pathway  Pathway Diagram
 BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway antibodies  BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
Diseases associated with DBP blocking peptideOrgans/Tissues associated with DBP blocking peptide
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5777 publications with DBP and Cardiovascular Diseases
 Hypertension Antibodies  >5704 publications with DBP and Hypertension
 Heart Diseases Antibodies  >1121 publications with DBP and Heart Diseases
 Kidney Diseases Antibodies  >508 publications with DBP and Kidney Diseases
 Hypertrophy Antibodies  >319 publications with DBP and Hypertrophy
 Atherosclerosis Antibodies  >265 publications with DBP and Atherosclerosis
 Cardiomegaly Antibodies  >205 publications with DBP and Cardiomegaly
 Inflammation Antibodies  >203 publications with DBP and Inflammation
 Weight Loss Antibodies  >181 publications with DBP and Weight Loss
 Edema Antibodies  >149 publications with DBP and Edema
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9537 publications with DBP and Blood
 Kidney Antibodies  >702 publications with DBP and Kidney
 Brain Antibodies  >334 publications with DBP and Brain
 Muscle Antibodies  >327 publications with DBP and Muscle
 Bone Antibodies  >248 publications with DBP and Bone
 Lung Antibodies  >197 publications with DBP and Lung
 Skin Antibodies  >191 publications with DBP and Skin
 Connective Tissue Antibodies  >177 publications with DBP and Connective Tissue
 Testis Antibodies  >170 publications with DBP and Testis
 Adipose Tissue Antibodies  >144 publications with DBP and Adipose Tissue
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