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DLK1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS153043 DLK1 blocking peptide
Unit / Price
0.05 mg  /  $135 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DLK1, Blocking Peptide

 Also Known As   

DLK1 Peptide

 Product Synonym Names    DLK; Protein delta homolog 1; pG2; DLK-1; delta-like 1 homolog (Drosophila)
 Product Gene Name   

DLK1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    DLK1 peptide (MBS153043) is used for blocking the activity of DLK1 antibody (MBS150208)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Western Blot Protocol    Western Blot Peptide Blocking Protocol
 OMIM    176290
 3D Structure    ModBase 3D Structure for P80370
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 Form/Format    Liquid
 Concentration    200 ug/mL (lot specific)
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 Species    Human
 Buffer    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
 Location    18 amino acid peptide near the carboxy terminus of human DLK1.
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 Preparation and Storage    Store DLK1 peptide at -20 degree C, stable for one year.
 Other Notes    Small volumes of DLK1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for DLK1 blocking peptide   

Blocking (BL)

 Application Notes for DLK1 blocking peptide    DLK1 peptide is used for blocking the activity of DLK1 antibody.
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NCBI/Uniprot data below describe general gene information for DLK1. It may not necessarily be applicable to this product.
 NCBI GI #    74136023
 NCBI GeneID    8788
 NCBI Accession #    NP_003827 [Other Products]
 NCBI GenBank Nucleotide #    NM_003836.5 [Other Products]
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 UniProt Primary Accession #    P80370 [Other Products]
 UniProt Secondary Accession #    P15803; Q96DW5 [Other Products]
 UniProt Related Accession #    P80370 [Other Products]
 Molecular Weight    33,067 Da
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 NCBI Official Full Name    protein delta homolog 1
 NCBI Official Synonym Full Names    delta-like 1 homolog (Drosophila)
 NCBI Official Symbol    DLK1 [Similar Products]
 NCBI Official Synonym Symbols   
DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1
[Similar Products]
 NCBI Protein Information    protein delta homolog 1; secredeltin; fetal antigen 1; preadipocyte factor 1
 UniProt Protein Name    Protein delta homolog 1
 UniProt Synonym Protein Names   
pG2Fetal antigen 1; FA1
 Protein Family    Protein
 UniProt Gene Name    DLK1 [Similar Products]
 UniProt Synonym Gene Names    DLK; DLK-1; FA1 [Similar Products]
 UniProt Entry Name    DLK1_HUMAN
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 NCBI Summary for DLK1    This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]
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 UniProt Comments for DLK1    DLK1: May have a role in neuroendocrine differentiation. Monomer. Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: extracellular space; integral to membrane; external side of plasma membrane

Biological Process: Notch signaling pathway; regulation of gene expression; embryonic skeletal development; multicellular organismal development; negative regulation of Notch signaling pathway; cell differentiation; post-embryonic development
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 Research Articles on DLK1    1. Pregnancies complicated by gestational diabetes mellitus have decreased fetal pref-1 concentrations compared to normal pregnancies
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DLK1 blocking peptidePathways associated with DLK1 blocking peptide
 Reference Product  PubMed Publications
 MEG3 blocking peptide  >107 publications with DLK1 and MEG3
 DIO3 blocking peptide  >100 publications with DLK1 and DIO3
 NOTCH1 blocking peptide  >68 publications with DLK1 and NOTCH1
 AFP blocking peptide  >6 publications with DLK1 and AFP
 FOXA2 blocking peptide  >5 publications with DLK1 and FOXA2
 CCNB1 blocking peptide  >1 publications with DLK1 and CCNB1
 Products by Pathway  Pathway Diagram
 Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies  Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 FBXW7 Mutants And NOTCH1 In Cancer Pathway antibodies  FBXW7 Mutants And NOTCH1 In Cancer Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By NOTCH Pathway antibodies  Signaling By NOTCH Pathway Diagram
 Signaling By NOTCH1 Pathway antibodies  Signaling By NOTCH1 Pathway Diagram
 Signaling By NOTCH1 HD Domain Mutants In Cancer Pathway antibodies  Signaling By NOTCH1 HD Domain Mutants In Cancer Pathway Diagram
Diseases associated with DLK1 blocking peptideOrgans/Tissues associated with DLK1 blocking peptide
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >38 publications with DLK1 and Liver Diseases
 Adenocarcinoma Antibodies  >23 publications with DLK1 and Adenocarcinoma
 Liver Neoplasms Antibodies  >22 publications with DLK1 and Liver Neoplasms
 Disease Models, Animal Antibodies  >21 publications with DLK1 and Disease Models, Animal
 Congenital Abnormalities Antibodies  >21 publications with DLK1 and Congenital Abnormalities
 Necrosis Antibodies  >20 publications with DLK1 and Necrosis
 Cardiovascular Diseases Antibodies  >19 publications with DLK1 and Cardiovascular Diseases
 Carcinoma, Hepatocellular Antibodies  >17 publications with DLK1 and Carcinoma, Hepatocellular
 Insulin Resistance Antibodies  >14 publications with DLK1 and Insulin Resistance
 Bone Marrow Diseases Antibodies  >14 publications with DLK1 and Bone Marrow Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >81 publications with DLK1 and Liver
 Embryonic Tissue Antibodies  >73 publications with DLK1 and Embryonic Tissue
 Brain Antibodies  >68 publications with DLK1 and Brain
 Bone Marrow Antibodies  >64 publications with DLK1 and Bone Marrow
 Placenta Antibodies  >32 publications with DLK1 and Placenta
 Lung Antibodies  >26 publications with DLK1 and Lung
 Nerve Antibodies  >22 publications with DLK1 and Nerve
 Kidney Antibodies  >19 publications with DLK1 and Kidney
 Heart Antibodies  >17 publications with DLK1 and Heart
 Pancreas Antibodies  >16 publications with DLK1 and Pancreas
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