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DNAL1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS824296 DNAL1 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DNAL1, Blocking Peptide

 Also Known As   

DNAL1 Blocking Peptide

 Product Synonym Names    C14orf168; Dynein light chain 1, axonemal
 Product Gene Name   

DNAL1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    DNAL1 peptide (MBS824296) is used for blocking the activity of DNAL1 antibody (MBS820725)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 614017
 3D Structure    ModBase 3D Structure for Q4LDG9
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 Host    Synthetic
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >85%
 Form/Format    Lyophilized powder
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 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of DNAL1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for DNAL1 blocking peptide

   The peptide is used to block Anti-DNAL1 Antibody reactivity.
 Applications Tested/Suitable for DNAL1 blocking peptide   

Blocking (BL)

 Application Notes for DNAL1 blocking peptide    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for DNAL1. It may not necessarily be applicable to this product.
 NCBI GI #    318984125
 NCBI GeneID    83544
 NCBI Accession #    NP_001188295.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001201366.1 [Other Products]
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 UniProt Primary Accession #    Q4LDG9 [Other Products]
 UniProt Secondary Accession #    Q5JPB7; Q9BS43; B2RD38 [Other Products]
 UniProt Related Accession #    Q4LDG9 [Other Products]
 Molecular Weight    17,096 Da
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 NCBI Official Full Name    dynein light chain 1, axonemal isoform 2
 NCBI Official Synonym Full Names    dynein, axonemal, light chain 1
 NCBI Official Symbol    DNAL1 [Similar Products]
 NCBI Official Synonym Symbols   
CILD16; C14orf168
[Similar Products]
 NCBI Protein Information    dynein light chain 1, axonemal
 UniProt Protein Name    Dynein light chain 1, axonemal
 Protein Family    Dynein
 UniProt Gene Name    DNAL1 [Similar Products]
 UniProt Synonym Gene Names    C14orf168 [Similar Products]
 UniProt Entry Name    DNAL1_HUMAN
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 NCBI Summary for DNAL1    This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
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 UniProt Comments for DNAL1    DNAL1: Defects in DNAL1 are the cause of primary ciliary dyskinesia type 16 (CILD16). A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the dynein light chain LC1-type family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q24.3

Disease: Ciliary Dyskinesia, Primary, 16
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 Research Articles on DNAL1    1. DNAL1 and MAP4 may exert their functions in the HIV life cycle at reverse transcription, prior to nuclear translocation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DNAL1 blocking peptidePathways associated with DNAL1 blocking peptide
 Reference Product  PubMed Publications
 DNAH5 blocking peptide  >3 publications with DNAL1 and DNAH5
 Products by Pathway  Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
Diseases associated with DNAL1 blocking peptideOrgans/Tissues associated with DNAL1 blocking peptide
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with DNAL1 and Cardiovascular Diseases
 Infertility, Male Antibodies  >3 publications with DNAL1 and Infertility, Male
 Infertility, Female Antibodies  >1 publications with DNAL1 and Infertility, Female
 Genital Diseases, Male Antibodies  >1 publications with DNAL1 and Genital Diseases, Male
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with DNAL1 and Lung
 Heart Antibodies  >2 publications with DNAL1 and Heart
 Brain Antibodies  >2 publications with DNAL1 and Brain
 Nerve Antibodies  >1 publications with DNAL1 and Nerve
 Prostate Antibodies  >1 publications with DNAL1 and Prostate
 Blood Antibodies  >1 publications with DNAL1 and Blood
 Embryonic Tissue Antibodies  >1 publications with DNAL1 and Embryonic Tissue
 Testis Antibodies  >1 publications with DNAL1 and Testis
 Ovary Antibodies  >1 publications with DNAL1 and Ovary
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