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IFITM1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS153141 IFITM1 blocking peptide
Unit / Price
0.05 mg  /  $140 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IFITM1, Blocking Peptide

★Popular Item★
 Also Known As   

IFITM1 Peptide

 Product Synonym Names    9-27; CD225; IFI17; LEU13; DSPA2a; Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; interferon induced transmembrane protein 1 (9-27)
 Product Gene Name   

IFITM1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    IFITM1 peptide (MBS153141) is used for blocking the activity of IFITM1 antibody (MBS150415)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Western Blot Protocol    Western Blot Peptide Blocking Protocol
 OMIM    604456
 3D Structure    ModBase 3D Structure for P13164
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 Form/Format    Liquid
 Concentration    200 ug/mL (lot specific)
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 Species    Human
 Buffer    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
 Location    14 amino acids near the carboxy terminus of human IFITM1.
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 Preparation and Storage    Store IFITM1 peptide at -20 degree C, stable for one year.
 Other Notes    Small volumes of IFITM1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for IFITM1 blocking peptide   

Blocking (BL)

 Application Notes for IFITM1 blocking peptide    IFITM1 peptide is used for blocking the activity of IFTIM1 antibody.
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NCBI/Uniprot data below describe general gene information for IFITM1. It may not necessarily be applicable to this product.
 NCBI GI #    150010589
 NCBI GeneID    8519
 NCBI Accession #    NP_003632 [Other Products]
 NCBI GenBank Nucleotide #    NM_003641.3 [Other Products]
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 UniProt Primary Accession #    P13164 [Other Products]
 UniProt Secondary Accession #    Q15322; Q53XZ0 [Other Products]
 UniProt Related Accession #    P13164; AAB25699 [Other Products]
 Molecular Weight    13,964 Da
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 NCBI Official Full Name    interferon-induced transmembrane protein 1
 NCBI Official Synonym Full Names    interferon induced transmembrane protein 1
 NCBI Official Symbol    IFITM1 [Similar Products]
 NCBI Official Synonym Symbols   
9-27; CD225; IFI17; LEU13; DSPA2a
[Similar Products]
 NCBI Protein Information    interferon-induced transmembrane protein 1; leu-13 antigen; interferon-induced protein 17; dispanin subfamily A member 2a; interferon-inducible protein 9-27
 UniProt Protein Name    Interferon-induced transmembrane protein 1
 UniProt Synonym Protein Names   
Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD_antigen: CD225
 Protein Family    Interferon-induced transmembrane protein
 UniProt Gene Name    IFITM1 [Similar Products]
 UniProt Synonym Gene Names    CD225; IFI17; DSPA2a [Similar Products]
 UniProt Entry Name    IFM1_HUMAN
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 UniProt Comments for IFITM1    IFITM1: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. Belongs to the CD225/Dispanin family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: protein binding; receptor signaling protein activity

Biological Process: negative regulation of cell proliferation; positive regulation of osteoblast differentiation; ossification; regulation of immune response; cell surface receptor linked signal transduction; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; response to virus; cytokine and chemokine mediated signaling pathway; defense response to virus; negative regulation of cell migration
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 Research Articles on IFITM1    1. IFITM1 could be a novel metastasis-promoting gene that enhances the metastatic phenotype in ovarian cancer via epigenetic transcriptional regulation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFITM1 blocking peptidePathways associated with IFITM1 blocking peptide
 Reference Product  PubMed Publications
 MX1 blocking peptide  >11 publications with IFITM1 and MX1
 IFIT1 blocking peptide  >7 publications with IFITM1 and IFIT1
 ISG15 blocking peptide  >6 publications with IFITM1 and ISG15
 IFI27 blocking peptide  >5 publications with IFITM1 and IFI27
 IFIT3 blocking peptide  >4 publications with IFITM1 and IFIT3
 IFI6 blocking peptide  >3 publications with IFITM1 and IFI6
 CD81 blocking peptide  >2 publications with IFITM1 and CD81
 IRF9 blocking peptide  >1 publications with IFITM1 and IRF9
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
Diseases associated with IFITM1 blocking peptideOrgans/Tissues associated with IFITM1 blocking peptide
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >8 publications with IFITM1 and Liver Diseases
 Adenocarcinoma Antibodies  >7 publications with IFITM1 and Adenocarcinoma
 Inflammation Antibodies  >6 publications with IFITM1 and Inflammation
 Skin Diseases Antibodies  >5 publications with IFITM1 and Skin Diseases
 Neoplasms, Experimental Antibodies  >3 publications with IFITM1 and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >3 publications with IFITM1 and Nervous System Diseases
 Breast Neoplasms Antibodies  >2 publications with IFITM1 and Breast Neoplasms
 Hematologic Diseases Antibodies  >2 publications with IFITM1 and Hematologic Diseases
 Liver Neoplasms Antibodies  >2 publications with IFITM1 and Liver Neoplasms
 Anemia Antibodies  >2 publications with IFITM1 and Anemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >20 publications with IFITM1 and Blood
 Liver Antibodies  >12 publications with IFITM1 and Liver
 Spleen Antibodies  >8 publications with IFITM1 and Spleen
 Brain Antibodies  >8 publications with IFITM1 and Brain
 Kidney Antibodies  >5 publications with IFITM1 and Kidney
 Lymph Node Antibodies  >4 publications with IFITM1 and Lymph Node
 Intestine Antibodies  >4 publications with IFITM1 and Intestine
 Heart Antibodies  >4 publications with IFITM1 and Heart
 Muscle Antibodies  >4 publications with IFITM1 and Muscle
 Uterus Antibodies  >4 publications with IFITM1 and Uterus
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