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IL32 blocking peptide :: IL-32 Blocking Peptide

Scan QR to view Datasheet Catalog #    MBS152680 IL32 blocking peptide
Unit / Price
0.05 mg  /  $135 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL-32 (IL32), Blocking Peptide

 Also Known As   

IL-32 Peptide

 Product Synonym Names    NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma; NK4; Interleukin-32; Natural killer cells protein 4; IL-32; interleukin 32
 Product Gene Name   

IL32 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    IL-32 peptide (MBS152680) is used for blocking the activity of IL-32 antibody (MBS150483)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Western Blot Protocol    Western Blot Peptide Blocking Protocol
 OMIM    606001
 3D Structure    ModBase 3D Structure for P24001
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 Form/Format    Liquid
 Concentration    200 ug/mL (lot specific)
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 Species    Human
 Buffer    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
 Location    15 amino acids near the carboxy terminus of human IL-32.
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 Preparation and Storage    Store IL-32 peptide at -20 degree C, stable for one year.
 Other Notes    Small volumes of IL32 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for IL32 blocking peptide   

Blocking (BL)

 Application Notes for IL32 blocking peptide    IL-32 peptide is used for blocking the activity of IL-32 antibody.
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NCBI/Uniprot data below describe general gene information for IL32. It may not necessarily be applicable to this product.
 NCBI GI #    14424787
 NCBI GeneID    9235
 NCBI Accession #    AAH09401 [Other Products]
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 UniProt Primary Accession #    P24001 [Other Products]
 UniProt Secondary Accession #    Q5VFH7; Q5VFH8; Q8WV38; Q96GK9; A6NNM0; A8MPX0; B4DJM1; B8Q191; D3DUB0; D3DUB2 [Other Products]
 UniProt Related Accession #    P24001 [Other Products]
 Molecular Weight    17,003 Da
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 NCBI Official Full Name    IL32 protein
 NCBI Official Synonym Full Names    interleukin 32
 NCBI Official Symbol    IL32 [Similar Products]
 NCBI Official Synonym Symbols   
NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma
[Similar Products]
 NCBI Protein Information    interleukin-32; interleukin-32 eta; interleukin-32 small; interleukin-32 theta; natural killer cells protein 4; natural killer cell transcript 4; tumor necrosis factor alpha-inducing factor
 UniProt Protein Name    Interleukin-32
 UniProt Synonym Protein Names   
Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
 Protein Family    Interleukin
 UniProt Gene Name    IL32 [Similar Products]
 UniProt Synonym Gene Names    NK4; TAIF; IL-32 [Similar Products]
 UniProt Entry Name    IL32_HUMAN
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 NCBI Summary for IL32    This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL32    IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space; membrane

Molecular Function: protein binding; cytokine activity

Biological Process: immune response; defense response; cell adhesion
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 Research Articles on IL32    1. IL-32alpha-mediated STAT3 S727 phosphorylation induced C/EBPalpha association, which inhibited PU.1 expression, and then resulted in the down-regulation of CD18 expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL32 blocking peptideDiseases associated with IL32 blocking peptide
 Reference Product  PubMed Publications
 IL18 blocking peptide  >5 publications with IL32 and IL18
 PTGS2 blocking peptide  >2 publications with IL32 and PTGS2
 IL1B blocking peptide  >2 publications with IL32 and IL1B
 CXCL2 blocking peptide  >1 publications with IL32 and CXCL2
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >65 publications with IL32 and Inflammation
 Necrosis Antibodies  >53 publications with IL32 and Necrosis
 Immune System Diseases Antibodies  >34 publications with IL32 and Immune System Diseases
 Lung Diseases Antibodies  >14 publications with IL32 and Lung Diseases
 Vascular Diseases Antibodies  >12 publications with IL32 and Vascular Diseases
 Carcinoma Antibodies  >11 publications with IL32 and Carcinoma
 Nervous System Diseases Antibodies  >9 publications with IL32 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >9 publications with IL32 and Cardiovascular Diseases
 Liver Diseases Antibodies  >7 publications with IL32 and Liver Diseases
 Lung Neoplasms Antibodies  >6 publications with IL32 and Lung Neoplasms
Organs/Tissues associated with IL32 blocking peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >64 publications with IL32 and Blood
 Lung Antibodies  >18 publications with IL32 and Lung
 Vascular Antibodies  >15 publications with IL32 and Vascular
 Bone Antibodies  >10 publications with IL32 and Bone
 Intestine Antibodies  >9 publications with IL32 and Intestine
 Liver Antibodies  >8 publications with IL32 and Liver
 Bone Marrow Antibodies  >7 publications with IL32 and Bone Marrow
 Stomach Antibodies  >6 publications with IL32 and Stomach
 Lymph Node Antibodies  >6 publications with IL32 and Lymph Node
 Brain Antibodies  >4 publications with IL32 and Brain
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