NP_079515
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,745 Da
NCBI Official Full Name
programmed cell death 1 ligand 2
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Synonym Symbols
B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2 [Similar Products]
NCBI Protein Information
programmed cell death 1 ligand 2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7 dendritic cell molecule
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
UniProt Synonym Gene Names
B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC [Similar Products]
UniProt Entry Name
PD1L2_HUMAN
UniProt Comments for PDCD1LG2
PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9p24.2
Cellular Component: plasma membrane; integral to membrane; endomembrane system
Biological Process: negative regulation of interleukin-10 production; negative regulation of interferon-gamma production; negative regulation of activated T cell proliferation; T cell costimulation; positive regulation of T cell proliferation; immune response
Research Articles on PDCD1LG2
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Disclaimer
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Products associated with PDCD1LG2 blocking peptide
Pathways associated with PDCD1LG2 blocking peptide
Diseases associated with PDCD1LG2 blocking peptide
Organs/Tissues associated with PDCD1LG2 blocking peptide
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