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PGLYRP4 blocking peptide

Scan QR to view Datasheet Catalog #    MBS9223515 PGLYRP4 blocking peptide
Unit / Price
0.1 mg  /  $155 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PGLYRP4, Blocking Peptide

★Popular Item★
 Also Known As   

PGLYRP4 Antibody (Center) Blocking Peptide

 Product Synonym Names    Peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta; PGLYRP4; PGRPIB
 Product Gene Name   

PGLYRP4 blocking peptide

[Similar Products]
 Product Synonym Gene Name    PGRPIB [Similar Products]
 Antibody/Peptide Pairs    PGLYRP4 peptide (MBS9223515) is used for blocking the activity of PGLYRP4 antibody (MBS9204259)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608198
 3D Structure    ModBase 3D Structure for Q96LB8
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 Clone Number    110811165
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 Form/Format    Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
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 Cellular Location    Secreted.
 Tissue Location    Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.
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 Preparation and Storage    Maintain refrigerated at 2-8C for up to 6 months. For long term storage store at -20 degree C.
 Other Notes    Small volumes of PGLYRP4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PGLYRP4 blocking peptide

   Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.
NCBI/Uniprot data below describe general gene information for PGLYRP4. It may not necessarily be applicable to this product.
 NCBI GI #    143811439
 NCBI GeneID    57115
 NCBI Accession #    Q96LB8.2 [Other Products]
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 UniProt Primary Accession #    Q96LB8 [Other Products]
 UniProt Secondary Accession #    Q3B822; Q3B823; Q5SY63; Q5SY64; Q9HD75; A8K838 [Other Products]
 UniProt Related Accession #    Q96LB8 [Other Products]
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 NCBI Official Full Name    Peptidoglycan recognition protein 4
 NCBI Official Synonym Full Names    peptidoglycan recognition protein 4
 NCBI Official Symbol    PGLYRP4 [Similar Products]
 NCBI Official Synonym Symbols   
PGRPIB; SBBI67; PGRP-Ibeta; PGLYRPIbeta
[Similar Products]
 NCBI Protein Information    peptidoglycan recognition protein 4
 UniProt Protein Name    Peptidoglycan recognition protein 4
 UniProt Synonym Protein Names   
Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta
 Protein Family    Peptidoglycan recognition protein
 UniProt Gene Name    PGLYRP4 [Similar Products]
 UniProt Synonym Gene Names    PGRPIB; PGLYRPIbeta; PGRP-I-beta [Similar Products]
 UniProt Entry Name    PGRP4_HUMAN
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 NCBI Summary for PGLYRP4    Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
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 UniProt Comments for PGLYRP4    PGLYRP4: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q21

Molecular Function: peptidoglycan binding; peptidoglycan receptor activity

Biological Process: defense response to Gram-positive bacterium; detection of bacterium
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 Research Articles on PGLYRP4    1. a significant induction of three PGLYRPs 2-4 in primary human corneal epithelial cells (HCECs) exposed to live or heat-killed Candida albicans, is reported.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PGLYRP4 blocking peptideOrgans/Tissues associated with PGLYRP4 blocking peptide
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with PGLYRP4 and Inflammation
 Weight Loss Antibodies  >1 publications with PGLYRP4 and Weight Loss
 Edema Antibodies  >1 publications with PGLYRP4 and Edema
 Body Weight Changes Antibodies  >1 publications with PGLYRP4 and Body Weight Changes
 Organ/Tissue Name  Pubmed Publications
 Esophagus Antibodies  >2 publications with PGLYRP4 and Esophagus
 Lung Antibodies  >1 publications with PGLYRP4 and Lung
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