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RUNX2 blocking peptide

Scan QR to view Datasheet Catalog #    MBS544403 RUNX2 blocking peptide
Unit / Price
0.25 mg Peptide  /  $250 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RUNX2, Blocking Peptide

 Also Known As   

RUNX2 Antibody Antigenic Blocking Peptide

 Product Synonym Names    Acute myeloid leukemia 3 protein; Alpha subunit 1; AML3; CBF alpha 1; CBFA1; CCD1; Cleidocranial dysplasia 1; Core binding factor runt domain alpha subunit 1; Core binding factor subunit alpha 1; Oncogene AML 3; OSF 2; Osteoblast specific transcription factor 2; PEBP2 alpha A; PEBP2A1; PEBP2A2; Polyomavirus enhancer-binding protein 2 alpha A subunit; Runt domain; Runt related transcription factor 2 antibody SL3 3 enhancer factor 1 alpha A subunit antibody
 Product Gene Name   

RUNX2 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    RUNX2 peptide (MBS544403) is used for blocking the activity of RUNX2 antibody (MBS540312)
 Antibody/Peptide Pairs    RUNX2 peptide (MBS544403) is used for blocking the activity of RUNX2 antibody (MBS544749)
 Antibody/Peptide Pairs    RUNX2 peptide (MBS544403) is used for blocking the activity of RUNX2 antibody (MBS544750)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Form/Format    Antigenic Blocking Peptide
 Concentration    Quantity: 250 ug; Volume: 100 ul (lot specific)
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 Immunogen    Synthetic Peptide
 Molecular Function    DNA-binding; Transcription Regulation
 Structure    Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain. DNA-binding is increased by heterodimerization. Interacts with XRCC6 (Ku70) and XRCC5 (Ku80). Interacts with HIVEP3. Interacts with IFI204. I
 Subcellular Location    Nucleus
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of RUNX2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for RUNX2 blocking peptide

   Antigenic Blocking Peptide Runt-related transcription factor 2 isoform 4 Antibody
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
 Applications Tested/Suitable for RUNX2 blocking peptide   

Immunodepletion, Immunocompetition

 Application Notes for RUNX2 blocking peptide    Western Blot: 1:500
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NCBI/Uniprot data below describe general gene information for RUNX2. It may not necessarily be applicable to this product.
 NCBI GI #    109071354
 NCBI GeneID    703331
 NCBI Accession #    XP_001100855.1 [Other Products]
 NCBI GenBank Nucleotide #    XM_001100855.2 [Other Products]
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 NCBI Official Symbol    LOC703331 [Similar Products]
 NCBI Official Synonym Symbols   
RUNX2
[Similar Products]
 NCBI Protein Information    runt-related transcription factor 2
 Protein Family    Runt-related transcription factor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RUNX2 blocking peptide
 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
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