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TRPV1 blocking peptide

Scan QR to view Datasheet Catalog #    MBS824306 TRPV1 blocking peptide
Unit / Price
1 mg  /  $160 +1 FREE 8GB USB
5 mg  /  $305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TRPV1, Blocking Peptide

★Popular Item★
 Also Known As   

TRPV1 Blocking Peptide

 Product Synonym Names    VR1; Transient receptor potential cation channel subfamily V member 1; TrpV1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
 Product Gene Name   

TRPV1 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    TRPV1 peptide (MBS824306) is used for blocking the activity of TRPV1 antibody (MBS820843)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602076
 3D Structure    ModBase 3D Structure for Q8NER1
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 Host    Synthetic
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >85%
 Form/Format    Lyophilized powder
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 Quality Control    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
 Entrez Gene    7442 (Human); 193034 (Mouse); 83810 (Rat)
 SwissProt    Q8NER1 (Human); Q704Y3 (Mouse); O35433 (Rat)
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 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of TRPV1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TRPV1 blocking peptide

   The peptide is used to block Anti-TRPV1 Antibody reactivity.
 Applications Tested/Suitable for TRPV1 blocking peptide   

Blocking (BL)

 Application Notes for TRPV1 blocking peptide    Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
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NCBI/Uniprot data below describe general gene information for TRPV1. It may not necessarily be applicable to this product.
 NCBI GI #    74315350
 NCBI GeneID    7442
 NCBI Accession #    NP_061197.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_018727.5 [Other Products]
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 UniProt Primary Accession #    Q8NER1 [Other Products]
 UniProt Secondary Accession #    Q3LU47; Q9H0G9; Q9H303; Q9H304; Q9NQ74; Q9NY22; A2RUA9 [Other Products]
 UniProt Related Accession #    Q8NER1 [Other Products]
 Molecular Weight    94,211 Da
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 NCBI Official Full Name    transient receptor potential cation channel subfamily V member 1
 NCBI Official Synonym Full Names    transient receptor potential cation channel, subfamily V, member 1
 NCBI Official Symbol    TRPV1 [Similar Products]
 NCBI Official Synonym Symbols   
VR1
[Similar Products]
 NCBI Protein Information    transient receptor potential cation channel subfamily V member 1; OTRPC1; capsaicin receptor; osm-9-like TRP channel 1; vanilloid receptor subtype 1; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b
 UniProt Protein Name    Transient receptor potential cation channel subfamily V member 1
 UniProt Synonym Protein Names   
Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
 Protein Family    Transient receptor potential cation channel subfamily
 UniProt Gene Name    TRPV1 [Similar Products]
 UniProt Synonym Gene Names    VR1; TrpV1; OTRPC1 [Similar Products]
 UniProt Entry Name    TRPV1_HUMAN
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 NCBI Summary for TRPV1    Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TRPV1    TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

Protein type: Channel, cation; Membrane protein, multi-pass; Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; integral to membrane; cell junction; intrinsic to plasma membrane

Molecular Function: calmodulin binding; transmembrane receptor activity; excitatory extracellular ligand-gated ion channel activity; calcium channel activity; calcium-release channel activity; phosphoprotein binding; ATP binding

Biological Process: cell surface receptor linked signal transduction; transport; chemosensory behavior; thermoception; transmembrane transport
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 Research Articles on TRPV1    1. There is now mounting evidence that TRPV1 receptors may be an important element in modulation of nociceptive information at the spinal cord level and represent an interesting target for analgesic therapy. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TRPV1 blocking peptidePathways associated with TRPV1 blocking peptide
 Reference Product  PubMed Publications
 NGF blocking peptide  >90 publications with TRPV1 and NGF
 GDNF blocking peptide  >40 publications with TRPV1 and GDNF
 SRC blocking peptide  >11 publications with TRPV1 and SRC
 PRKCE blocking peptide  >3 publications with TRPV1 and PRKCE
 TAC1 blocking peptide  >2 publications with TRPV1 and TAC1
 SYT9 blocking peptide  >1 publications with TRPV1 and SYT9
 Products by Pathway  Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Stimuli-sensing Channels Pathway antibodies  Stimuli-sensing Channels Pathway Diagram
 TRP Channels Pathway antibodies  TRP Channels Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway antibodies  Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway Diagram
 Trk Receptor Signaling Mediated By The MAPK Pathway antibodies  Trk Receptor Signaling Mediated By The MAPK Pathway Diagram
Diseases associated with TRPV1 blocking peptideOrgans/Tissues associated with TRPV1 blocking peptide
 Disease Name  Pubmed Publications
 Pain Antibodies  >1557 publications with TRPV1 and Pain
 Nervous System Diseases Antibodies  >1032 publications with TRPV1 and Nervous System Diseases
 Inflammation Antibodies  >729 publications with TRPV1 and Inflammation
 Hyperalgesia Antibodies  >522 publications with TRPV1 and Hyperalgesia
 Necrosis Antibodies  >85 publications with TRPV1 and Necrosis
 Hypertension Antibodies  >77 publications with TRPV1 and Hypertension
 Urinary Bladder Diseases Antibodies  >65 publications with TRPV1 and Urinary Bladder Diseases
 Edema Antibodies  >65 publications with TRPV1 and Edema
 Heart Diseases Antibodies  >58 publications with TRPV1 and Heart Diseases
 Obesity Antibodies  >44 publications with TRPV1 and Obesity
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1008 publications with TRPV1 and Nerve
 Brain Antibodies  >541 publications with TRPV1 and Brain
 Blood Antibodies  >395 publications with TRPV1 and Blood
 Skin Antibodies  >329 publications with TRPV1 and Skin
 Muscle Antibodies  >292 publications with TRPV1 and Muscle
 Vascular Antibodies  >237 publications with TRPV1 and Vascular
 Lung Antibodies  >141 publications with TRPV1 and Lung
 Intestine Antibodies  >132 publications with TRPV1 and Intestine
 Kidney Antibodies  >123 publications with TRPV1 and Kidney
 Mouth Antibodies  >100 publications with TRPV1 and Mouth
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