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TSH blocking peptide :: TSH beta Blocking Peptide

Scan QR to view Datasheet Catalog #    MBS544626 TSH blocking peptide
Unit / Price
0.25 mg Peptide  /  $250 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TSH beta, Blocking Peptide

 Also Known As   

TSH beta Antibody Antigenic Blocking Peptide

 Product Synonym Names    CHNG4; Thyroid stimulating hormone beta subunit; Thyrotropin beta subunit; TSHB antibody
 Product Gene Name   

TSH blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    TSH beta peptide (MBS544626) is used for blocking the activity of TSH beta antibody (MBS5400185)
 Antibody/Peptide Pairs    TSH beta peptide (MBS544626) is used for blocking the activity of TSH beta antibody (MBS5400186)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    188540
 3D Structure    ModBase 3D Structure for P01222
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 Form/Format    Antigenic Blocking Peptide
 Concentration    Quantity: 250 ug; Volume: 100 ul (lot specific)
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 Immunogen    Synthetic Peptide
 Determinant    C-epitope
 Molecular Function    hormone activity
 Subcellular Location    Secreted
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of TSH blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TSH blocking peptide

   Antigenic Blocking Peptide Thyroid stimulating hormone, beta Antibody C-epitope
Indespensable for the control of thyroid structure and metabolism.
 Applications Tested/Suitable for TSH blocking peptide   

Immunocompeition, Immunodepletion

 Application Notes for TSH blocking peptide    Confocal Microscopy||1:250
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Western Blot: 1:500
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NCBI/Uniprot data below describe general gene information for TSH. It may not necessarily be applicable to this product.
 NCBI GI #    47479818
 NCBI GeneID    7252
 NCBI Accession #    AAH69298.1 [Other Products]
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 UniProt Primary Accession #    P01222 [Other Products]
 UniProt Secondary Accession #    Q16163; B1AKP0 [Other Products]
 UniProt Related Accession #    P01222 [Other Products]
 Molecular Weight    10,624 Da
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 NCBI Official Full Name    Thyroid stimulating hormone, beta
 NCBI Official Synonym Full Names    thyroid stimulating hormone beta
 NCBI Official Symbol    TSHB [Similar Products]
 NCBI Official Synonym Symbols   
TSH-B; TSH-BETA
[Similar Products]
 NCBI Protein Information    thyrotropin subunit beta
 UniProt Protein Name    Thyrotropin subunit beta
 UniProt Synonym Protein Names   
Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; INN: Thyrotropin alfa
 Protein Family    Temperature-sensitive hemagglutinin tsh autotransporter
 UniProt Gene Name    TSHB [Similar Products]
 UniProt Synonym Gene Names    TSH-B; TSH-beta [Similar Products]
 UniProt Entry Name    TSHB_HUMAN
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 NCBI Summary for TSH    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
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 UniProt Comments for TSH    TSHB: Indispensable for the control of thyroid structure and metabolism. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: anatomical structure morphogenesis; cell-cell signaling; G-protein coupled receptor protein signaling pathway; peptide hormone processing; response to calcium ion; response to estrogen stimulus; response to vitamin A

Disease: Hypothyroidism, Congenital, Nongoitrous, 4
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 Research Articles on TSH    1. analysis of a single nucleotide substitution in TSHbeta related to clinical euthyroidism [family case report]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TSH blocking peptideDiseases associated with TSH blocking peptide
 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 Hormone Ligand-binding Receptors Pathway antibodies  Hormone Ligand-binding Receptors Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Thyroid Diseases Antibodies  >15 publications with TSH and Thyroid Diseases
 Hypothyroidism Antibodies  >15 publications with TSH and Hypothyroidism
 Nervous System Diseases Antibodies  >3 publications with TSH and Nervous System Diseases
 Liver Diseases Antibodies  >3 publications with TSH and Liver Diseases
 Hyperplasia Antibodies  >2 publications with TSH and Hyperplasia
 Carcinoma, Hepatocellular Antibodies  >2 publications with TSH and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with TSH and Liver Neoplasms
 Brain Diseases Antibodies  >2 publications with TSH and Brain Diseases
 Fatty Liver Antibodies  >1 publications with TSH and Fatty Liver
 Breast Neoplasms Antibodies  >1 publications with TSH and Breast Neoplasms
Organs/Tissues associated with TSH blocking peptide
 Organ/Tissue Name  Pubmed Publications
 Pituitary Gland Antibodies  >19 publications with TSH and Pituitary Gland
 Pancreas Antibodies  >2 publications with TSH and Pancreas
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