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TSLP blocking peptide

Scan QR to view Datasheet Catalog #    MBS152395 TSLP blocking peptide
Unit / Price
0.05 mg  /  $135 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TSLP, Blocking Peptide

 Also Known As   

TSLP Peptide

 Product Synonym Names    Thymic stromal lymphopoietin; thymic stromal lymphopoietin
 Product Gene Name   

TSLP blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    TSLP peptide (MBS152395) is used for blocking the activity of TSLP antibody (MBS150090)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Western Blot Protocol    Western Blot Peptide Blocking Protocol
 OMIM    607003
 3D Structure    ModBase 3D Structure for Q969D9
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 Form/Format    Liquid
 Concentration    200 ug/mL (lot specific)
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 Species    Mouse
 Buffer    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
 Location    20 amino acids near the center of mouse TSLP
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 Preparation and Storage    Store TSLP peptide at -20 degree C, stable for one year.
 Other Notes    Small volumes of TSLP blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for TSLP blocking peptide   

Blocking (BL)

 Application Notes for TSLP blocking peptide    TSLP peptide is used for blocking the activity of TSLP antibody.
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NCBI/Uniprot data below describe general gene information for TSLP. It may not necessarily be applicable to this product.
 NCBI GI #    14719428
 NCBI GeneID    85480
 NCBI Accession #    NP_149024 [Other Products]
 NCBI GenBank Nucleotide #    NM_033035.4 [Other Products]
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 UniProt Primary Accession #    Q969D9 [Other Products]
 UniProt Secondary Accession #    Q8IW99 [Other Products]
 UniProt Related Accession #    Q969D9 [Other Products]
 Molecular Weight    18,141 Da
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 NCBI Official Full Name    thymic stromal lymphopoietin isoform 1
 NCBI Official Synonym Full Names    thymic stromal lymphopoietin
 NCBI Official Symbol    TSLP [Similar Products]
 NCBI Protein Information    thymic stromal lymphopoietin
 UniProt Protein Name    Thymic stromal lymphopoietin
 Protein Family    Thymic stromal lymphopoietin
 UniProt Gene Name    TSLP [Similar Products]
 UniProt Entry Name    TSLP_HUMAN
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 NCBI Summary for TSLP    This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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 UniProt Comments for TSLP    TSLP: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q22.1

Cellular Component: extracellular space

Molecular Function: cytokine activity
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 Research Articles on TSLP    1. these results support epistasis between SPINK5 and TSLP, which contributes to childhood asthma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TSLP blocking peptidePathways associated with TSLP blocking peptide
 Reference Product  PubMed Publications
 CRLF2 blocking peptide  >62 publications with TSLP and CRLF2
 TNFSF4 blocking peptide  >35 publications with TSLP and TNFSF4
 IL13 blocking peptide  >33 publications with TSLP and IL13
 FOXP3 blocking peptide  >27 publications with TSLP and FOXP3
 CCL17 blocking peptide  >25 publications with TSLP and CCL17
 IL4 blocking peptide  >10 publications with TSLP and IL4
 IL7R blocking peptide  >6 publications with TSLP and IL7R
 IL9 blocking peptide  >2 publications with TSLP and IL9
 IL21 blocking peptide  >1 publications with TSLP and IL21
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 TSLP Signaling Pathway antibodies  TSLP Signaling Pathway Diagram
Diseases associated with TSLP blocking peptideOrgans/Tissues associated with TSLP blocking peptide
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >316 publications with TSLP and Inflammation
 Asthma Antibodies  >218 publications with TSLP and Asthma
 Dermatitis, Atopic Antibodies  >169 publications with TSLP and Dermatitis, Atopic
 Lung Diseases Antibodies  >145 publications with TSLP and Lung Diseases
 Disease Models, Animal Antibodies  >75 publications with TSLP and Disease Models, Animal
 Necrosis Antibodies  >66 publications with TSLP and Necrosis
 Hyperplasia Antibodies  >18 publications with TSLP and Hyperplasia
 Fibrosis Antibodies  >17 publications with TSLP and Fibrosis
 Eosinophilic Esophagitis Antibodies  >13 publications with TSLP and Eosinophilic Esophagitis
 Cardiovascular Diseases Antibodies  >10 publications with TSLP and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >170 publications with TSLP and Skin
 Lung Antibodies  >142 publications with TSLP and Lung
 Bone Marrow Antibodies  >37 publications with TSLP and Bone Marrow
 Eye Antibodies  >12 publications with TSLP and Eye
 Brain Antibodies  >7 publications with TSLP and Brain
 Connective Tissue Antibodies  >1 publications with TSLP and Connective Tissue
 Thyroid Antibodies  >1 publications with TSLP and Thyroid
 Salivary Gland Antibodies  >1 publications with TSLP and Salivary Gland
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