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TYW3 blocking peptide

Scan QR to view Datasheet Catalog #    MBS153117 TYW3 blocking peptide
Unit / Price
0.05 mg  /  $135 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TYW3, Blocking Peptide

 Also Known As   

TYW3 Peptide

 Product Synonym Names    C1orf171; C1orf171; tRNA wybutosine-synthesizing protein 3 homolog; tRNA-yW-synthesizing protein 3; tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
 Product Gene Name   

TYW3 blocking peptide

[Similar Products]
 Antibody/Peptide Pairs    TYW3 peptide (MBS153117) is used for blocking the activity of TYW3 antibody (MBS150652)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Western Blot Protocol    Western Blot Peptide Blocking Protocol
 OMIM    611245
 3D Structure    ModBase 3D Structure for Q6IPR3
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 Form/Format    Liquid
 Concentration    200 ug/mL (lot specific)
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 Species    Human
 Buffer    PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
 Location    17 amino acids near the center of human TYW3.
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 Preparation and Storage    Store TYW3 peptide at -20 degree C, stable for one year.
 Other Notes    Small volumes of TYW3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for TYW3 blocking peptide   

Blocking (BL)

 Application Notes for TYW3 blocking peptide    TYW3 peptide is used for blocking the activity of TYW3 antibody.
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NCBI/Uniprot data below describe general gene information for TYW3. It may not necessarily be applicable to this product.
 NCBI GI #    42734381
 NCBI GeneID    127253
 NCBI Accession #    NP_612476.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_138467.2 [Other Products]
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 UniProt Primary Accession #    Q6IPR3 [Other Products]
 UniProt Secondary Accession #    Q5HYJ0; Q8N7L1; B4DSP9; E9PGR7 [Other Products]
 UniProt Related Accession #    Q6IPR3 [Other Products]
 Molecular Weight    26,104 Da
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 NCBI Official Full Name    tRNA wybutosine-synthesizing protein 3 homolog isoform 1
 NCBI Official Synonym Full Names    tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
 NCBI Official Symbol    TYW3 [Similar Products]
 NCBI Official Synonym Symbols   
C1orf171
[Similar Products]
 NCBI Protein Information    tRNA wybutosine-synthesizing protein 3 homolog; tRNA-yW-synthesizing protein 3; tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase
 UniProt Protein Name    tRNA wybutosine-synthesizing protein 3 homolog
 UniProt Synonym Protein Names   
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase
 Protein Family    tRNA wybutosine-synthesizing protein
 UniProt Gene Name    TYW3 [Similar Products]
 UniProt Synonym Gene Names    C1orf171; tRNA-yW-synthesizing protein 3 [Similar Products]
 UniProt Entry Name    TYW3_HUMAN
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 NCBI Summary for TYW3    Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]
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 UniProt Comments for TYW3    TYW3: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TYW3 family.

Protein type: Methyltransferase; EC 2.1.1.282

Chromosomal Location of Human Ortholog: 1p31.1

Molecular Function: methyltransferase activity

Biological Process: methylation; tRNA processing
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TYW3 blocking peptidePathways associated with TYW3 blocking peptide
 Reference Product  PubMed Publications
 TYW1 blocking peptide  >3 publications with TYW3 and TYW1
 Products by Pathway  Pathway Diagram
 7-(3-amino-3-carboxypropyl)-wyosine Biosynthesis Pathway antibodies  7-(3-amino-3-carboxypropyl)-wyosine Biosynthesis Pathway Diagram
 Wybutosine Biosynthesis Pathway antibodies  Wybutosine Biosynthesis Pathway Diagram
Diseases associated with TYW3 blocking peptideOrgans/Tissues associated with TYW3 blocking peptide
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >1 publications with TYW3 and Insulin Resistance
 Inflammation Antibodies  >1 publications with TYW3 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with TYW3 and Blood
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