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WFIKKN2 blocking peptide

Scan QR to view Datasheet Catalog #    MBS9223414 WFIKKN2 blocking peptide
Unit / Price
0.1 mg  /  $155 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WFIKKN2, Blocking Peptide

 Also Known As   

WFIKKN2 Antibody (C-term) Blocking Peptide

 Product Synonym Names    WAP; Kazal; immunoglobulin; Kunitz and NTR domain-containing protein 2; Growth and differentiation factor-associated serum protein 1; GASP-1; hGASP-1; WAP; follistatin; immunoglobulin; Kunitz and NTR domain-containing-related protein; WFIKKN-related protein; WFIKKN2; GASP1; WFIKKNRP
 Product Gene Name   

WFIKKN2 blocking peptide

[Similar Products]
 Product Synonym Gene Name    GASP1; WFIKKNRP [Similar Products]
 Antibody/Peptide Pairs    WFIKKN2 peptide (MBS9223414) is used for blocking the activity of WFIKKN2 antibody (MBS9205555)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    610895
 3D Structure    ModBase 3D Structure for Q8TEU8
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 Form/Format    Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
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 Cellular Location    Secreted.
 Tissue Location    Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
 Other Notes    Small volumes of WFIKKN2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for WFIKKN2 blocking peptide

   Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity).
NCBI/Uniprot data below describe general gene information for WFIKKN2. It may not necessarily be applicable to this product.
 NCBI GI #    74716081
 NCBI GeneID    124857
 NCBI Accession #    Q8TEU8.1 [Other Products]
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 UniProt Primary Accession #    Q8TEU8 [Other Products]
 UniProt Secondary Accession #    Q6UXZ9 [Other Products]
 UniProt Related Accession #    Q8TEU8 [Other Products]
 Molecular Weight    63,941 Da
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 NCBI Official Full Name    WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
 NCBI Official Synonym Full Names    WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
 NCBI Official Symbol    WFIKKN2 [Similar Products]
 NCBI Official Synonym Symbols   
GASP-1; WFDC20B; hGASP-1; WFIKKNRP
[Similar Products]
 NCBI Protein Information    WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
 UniProt Protein Name    WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2
 UniProt Synonym Protein Names   
Growth and differentiation factor-associated serum protein 1; GASP-1; hGASP-1; WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein; WFIKKN-related protein
 Protein Family    WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein
 UniProt Gene Name    WFIKKN2 [Similar Products]
 UniProt Synonym Gene Names    GASP1; WFIKKNRP; GASP-1; hGASP-1 [Similar Products]
 UniProt Entry Name    WFKN2_HUMAN
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 NCBI Summary for WFIKKN2    The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008]
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 UniProt Comments for WFIKKN2    WFIKKN2: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin. Belongs to the WFIKKN family.

Protein type: Secreted; Secreted, signal peptide; Inhibitor

Chromosomal Location of Human Ortholog: 17q21.33
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 Research Articles on WFIKKN2    1. Data suggest that myostatin binding to its receptor (activin receptors type II) can be blocked by WFIKKN1 but not WFIKKN2; various forms of myostatin (promyostatin, myostatin pro-domain, and latent/processed myostatin) bind WFIKKN1 but not WFIKKN2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to WFIKKN2 Antibody (C-term) Blocking Peptide
 Catalog #  Product Name  Catalog #  Product Name
 MBS9393464  Goose WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit  MBS9393471  Porcine WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit
 MBS8223658  WFIKKN2 siRNA (Human)  MBS9393467  Hamster WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit
 MBS9393470  Pigeon WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit  MBS9393474  Sheep WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit
 MBS109284  Mouse WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit  MBS9393458  Camel WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit
 MBS9393457  Chicken WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit  MBS9393462  Duck WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 2 (WFIKKN2) ELISA Kit
Organs/Tissues associated with WFIKKN2 blocking peptide
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >5 publications with WFIKKN2 and Muscle
 Brain Antibodies  >1 publications with WFIKKN2 and Brain
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