AAH69057
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,485 Da
NCBI Official Full Name
zinc finger, MYM-type 3, isoform CRA_a
NCBI Official Synonym Full Names
zinc finger, MYM-type 3
NCBI Official Synonym Symbols
MYM; XFIM; ZNF261; DXS6673E; ZNF198L2 [Similar Products]
NCBI Protein Information
zinc finger MYM-type protein 3; zinc finger protein 261
UniProt Protein Name
Zinc finger MYM-type protein 3
UniProt Synonym Protein Names
Zinc finger protein 261
UniProt Synonym Gene Names
UniProt Entry Name
ZMYM3_HUMAN
NCBI Summary for ZMYM3
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
UniProt Comments for ZMYM3
ZNF261: Plays a role in the regulation of cell morphology and cytoskeletal organization. A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?). 3 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: nucleus
Molecular Function: DNA binding; zinc ion binding
Biological Process: multicellular organismal development; regulation of cell morphogenesis; cytoskeleton organization and biogenesis
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Diseases associated with ZMYM3 blocking peptide
Organs/Tissues associated with ZMYM3 blocking peptide
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