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ADAM10 clia kit :: Rat A Disintegrin And Metalloprotease 10 (ADAM10) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2001237 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $315 +1 FREE 8GB USB
48-Strip-Wells  /  $620 +1 FREE 8GB USB
96-Strip-Wells  /  $845 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,440 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,210 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloprotease 10 (ADAM10), CLIA Kit

★Popular Item★
 Also Known As   

A Disintegrin And Metalloprotease 10 (ADAM10) CLIA Kit

 Product Synonym Names    CD156-C; CD156c; MADM; Kuz; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloprotease
 Product Gene Name   

ADAM10 clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    277600
 3D Structure    ModBase 3D Structure for Q9H324
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of A Disintegrin And Metalloprotease 10 (ADAM10).
No significant cross-reactivity or interference between A Disintegrin And Metalloprotease 10 (ADAM10) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Serum, Plasma, Tissue homogenates and Other Biological Fluids
 Detection Range    6.86-5,000pg/mL
 Sensitivity    < 3.13pg/mL
 Application    Chemiluminescent immunoassay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level A Disintegrin And Metalloprotease 10 (ADAM10) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level A Disintegrin And Metalloprotease 10 (ADAM10) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAM10 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ADAM10 clia kit

   The microplate provided in this kit has been pre-coated with an antibody specific to A Disintegrin And Metalloprotease 10 (ADAM10). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to A Disintegrin And Metalloprotease 10 (ADAM10). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the A Disintegrin And Metalloprotease 10 (ADAM10) level in the sample or standard.;
 Product Categories/Family for ADAM10 clia kit    Enzyme & Kinase; Tumor immunity; Infection immunity; Cardiovascular biology
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 Typical Testing Data/Standard Curve (for reference only) of ADAM10 clia kit    ADAM10 clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2001237. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ADAM10. It may not necessarily be applicable to this product.
 NCBI GI #    537544566
 NCBI GeneID    81794
 NCBI Accession #    NP_112219.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_030957.3 [Other Products]
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 UniProt Primary Accession #    Q9H324 [Other Products]
 UniProt Secondary Accession #    M0QZE4 [Other Products]
 UniProt Related Accession #    Q9H324 [Other Products]
 Molecular Weight    62,530 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 10
 NCBI Official Symbol    ADAMTS10 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 10
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 10
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAMTS10 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 10; ADAM-TS10; ADAMTS-10 [Similar Products]
 UniProt Entry Name    ATS10_HUMAN
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 NCBI Summary for ADAM10    This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAM10    ADAMTS10: Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues. Defects in ADAMTS10 are the cause of Weill-Marchesani syndrome 1 (WMS1). WMS1 is a rare connective tissue disorder characterized by short stature, brachydactyly, joint stiffness, and eye abnormalities including microspherophakia, ectopia lentis, severe myopia and glaucoma.

Protein type: EC 3.4.24.-; Protease; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular matrix; microfibril

Molecular Function: protein binding; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis

Disease: Weill-marchesani Syndrome 1
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 Research Articles on ADAM10    1. These findings support the Gly661Arg mutation of ADAMTS10 as the likely cause of POAG in beagles.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADAM10 clia kitDiseases associated with ADAM10 clia kit
 Reference Product  PubMed Publications
 FBN1 clia kit  >8 publications with ADAM10 and FBN1
 LTBP1 clia kit  >1 publications with ADAM10 and LTBP1
 Disease Name  Pubmed Publications
 Weill-Marchesani Syndrome Antibodies  >13 publications with ADAM10 and Weill-Marchesani Syndrome
 Pregnancy Complications Antibodies  >1 publications with ADAM10 and Pregnancy Complications
 Kidney Diseases Antibodies  >1 publications with ADAM10 and Kidney Diseases
 Heart Diseases Antibodies  >1 publications with ADAM10 and Heart Diseases
Organs/Tissues associated with ADAM10 clia kit
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >9 publications with ADAM10 and Eye
 Skin Antibodies  >3 publications with ADAM10 and Skin
 Blood Antibodies  >2 publications with ADAM10 and Blood
 Heart Antibodies  >2 publications with ADAM10 and Heart
 Kidney Antibodies  >2 publications with ADAM10 and Kidney
 Nerve Antibodies  >1 publications with ADAM10 and Nerve
 Lung Antibodies  >1 publications with ADAM10 and Lung
 Embryonic Tissue Antibodies  >1 publications with ADAM10 and Embryonic Tissue
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