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ABCG1 clia kit :: Human ABCG1 (ATP Binding Cassette Transporter G1) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2530936
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCG1 (ATP Binding Cassette Transporter G1), CLIA Kit

 Also Known As   

Human ABCG1 (ATP Binding Cassette Transporter G1) CLIA Kit

 Product Gene Name   

ABCG1 clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    603076
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant ABCG1. No significant cross-reactivity or interference between ABCG1 and analogues was observed.
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 Assay Type    Sandwich
 Detection Range    31.25-2000pg/mL
 Sensitivity    Min: 18.75pg/mL; Max: 2000pg/mL
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ABCG1 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ABCG1 clia kit

   Intended Uses: This CLIA kit applies to the in vitro quantitative determination of ABCG1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to ABCG1. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ABCG1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ABCG1, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of ABCG1. You can calculate the concentration of ABCG1 in the samples by comparing the RLU value of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of ABCG1 clia kit    ABCG1 clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2530936. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ABCG1. It may not necessarily be applicable to this product.
 NCBI GI #    16304311
 NCBI GeneID    9619
 NCBI Accession #    AAL06598.1 [Other Products]
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 UniProt Secondary Accession #    Q86SU8; Q96L76; Q9BXK6; Q9BXK7; Q9BXK8; Q9BXK9; Q9BXL0; Q9BXL1; Q9BXL2; Q9BXL3; Q9BXL4 [Other Products]
 UniProt Related Accession #    P45844 [Other Products]
 Molecular Weight    86,628 Da
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 NCBI Official Full Name    ATP-binding cassette transporter G1
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family G (WHITE), member 1
 NCBI Official Symbol    ABCG1 [Similar Products]
 NCBI Official Synonym Symbols   
ABC8; WHITE1
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family G member 1
 UniProt Protein Name    ATP-binding cassette sub-family G member 1
 UniProt Synonym Protein Names   
ATP-binding cassette transporter 8; White protein homolog
 Protein Family    ABC transporter G family
 UniProt Gene Name    ABCG1 [Similar Products]
 UniProt Synonym Gene Names    ABC8; WHT1 [Similar Products]
 UniProt Entry Name    ABCG1_HUMAN
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 NCBI Summary for ABCG1    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCG1    ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ABC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: endoplasmic reticulum membrane; endosome; external side of plasma membrane; Golgi apparatus; Golgi membrane; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; mitochondrion; nucleoplasm; plasma membrane; recycling endosome

Molecular Function: ADP binding; ATP binding; cholesterol binding; cholesterol transporter activity; phospholipid binding; phospholipid transporter activity; protein binding; protein dimerization activity; protein heterodimerization activity; protein homodimerization activity; sterol-transporting ATPase activity; toxin transporter activity

Biological Process: amyloid precursor protein catabolic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; detection of hormone stimulus; intracellular cholesterol transport; lipoprotein metabolic process; phospholipid efflux; phospholipid homeostasis; positive regulation of cholesterol biosynthetic process; regulation of transcription, DNA-dependent; response to high density lipoprotein stimulus; response to lipid; response to organic substance; reverse cholesterol transport; transmembrane transport
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 Research Articles on ABCG1    1. Hyperalphalipoproteinemics present a decrease in hsa-miR-33a and higher mRNA expression of ABCA1 and ABCG1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ABCG1 clia kitPathways associated with ABCG1 clia kit
 Reference Product  PubMed Publications
 SCARB1 clia kit  >83 publications with ABCG1 and SCARB1
 ABCG4 clia kit  >42 publications with ABCG1 and ABCG4
 APOA1 clia kit  >37 publications with ABCG1 and APOA1
 NPC1 clia kit  >13 publications with ABCG1 and NPC1
 NR1H3 clia kit  >7 publications with ABCG1 and NR1H3
 NR1H2 clia kit  >4 publications with ABCG1 and NR1H2
 RARS clia kit  >2 publications with ABCG1 and RARS
 COL4A3BP clia kit  >1 publications with ABCG1 and COL4A3BP
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters In Lipid Homeostasis Pathway antibodies  ABC Transporters In Lipid Homeostasis Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Nuclear Receptors In Lipid Metabolism And Toxicity Pathway antibodies  Nuclear Receptors In Lipid Metabolism And Toxicity Pathway Diagram
Organs/Tissues associated with ABCG1 clia kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >342 publications with ABCG1 and Liver
 Blood Antibodies  >236 publications with ABCG1 and Blood
 Brain Antibodies  >61 publications with ABCG1 and Brain
 Lung Antibodies  >43 publications with ABCG1 and Lung
 Muscle Antibodies  >39 publications with ABCG1 and Muscle
 Kidney Antibodies  >27 publications with ABCG1 and Kidney
 Intestine Antibodies  >23 publications with ABCG1 and Intestine
 Connective Tissue Antibodies  >13 publications with ABCG1 and Connective Tissue
 Pancreas Antibodies  >12 publications with ABCG1 and Pancreas
 Spleen Antibodies  >12 publications with ABCG1 and Spleen
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