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ACTH clia kit :: Human ACTH (Adrenocorticotropic Hormone) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2532574 ACTH clia kit
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACTH (Adrenocorticotropic Hormone), CLIA Kit

 Also Known As   

Human ACTH (Adrenocorticotropic Hormone) CLIA Kit

 Product Synonym Names    Corticotropin; POMC; Adrenocorticotropin
 Product Gene Name   

ACTH clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Human
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 Detection Range    15.625~1000pg/mL
 Sensitivity    9.375pg/mL
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ACTH clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ACTH clia kit

   This CLIA kit uses Competitive-CLIA as the method. The microtiter plate provided in this kit has been pre-coated with Human ACTH. During the reaction, Human ACTH in the sample or standard competes with a fixed amount of Human ACTH on the solid phase supporter for sites on the Biotinylated Detection Ab specific to Human ACTH. Excess conjugate and unbound sample or standard are washed from the plate, and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The Relative light unit(RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is negatively associated with the concentration of Human ACTH. You can calculate the concentration of Human ACTH in the samples by comparing the RLU of the samples to the standard curve.
NCBI/Uniprot data below describe general gene information for ACTH. It may not necessarily be applicable to this product.
 NCBI GI #    191659
 NCBI GeneID    18976
 NCBI Accession #    AAA37169.1 [Other Products]
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 UniProt Secondary Accession #    P01200; Q544U4 [Other Products]
 UniProt Related Accession #    P01193 [Other Products]
 Molecular Weight    26,707 Da
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 NCBI Official Full Name    adrenocorticotropic hormone, partial
 NCBI Official Synonym Full Names    pro-opiomelanocortin-alpha
 NCBI Official Symbol    Pomc [Similar Products]
 NCBI Official Synonym Symbols   
BE; Npp; ACTH; Clip; Pomc1; Pomc-1; Beta-LPH; alphaMSH; beta-MSH; Gamma-LPH; alpha-MSH; gamma-MSH
[Similar Products]
 NCBI Protein Information    pro-opiomelanocortin
 UniProt Protein Name    Pro-opiomelanocortin
 UniProt Synonym Protein Names   
Corticotropin-lipotropin
 UniProt Gene Name    Pomc [Similar Products]
 UniProt Synonym Gene Names    Pomc1; POMC; ACTH; CLIP [Similar Products]
 UniProt Entry Name    COLI_MOUSE
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 NCBI Summary for ACTH    This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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 UniProt Comments for ACTH    POMC: ACTH stimulates the adrenal glands to release cortisol. Defects in POMC may be associated with susceptibility to obesity (OBESITY). It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Defects in POMC are the cause of pro-opiomelanocortinin deficiency (POMCD). Affected individuals present early-onset obesity, adrenal insufficiency and red hair. Belongs to the POMC family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; peroxisomal matrix; cytoplasm; extracellular region; secretory granule

Molecular Function: type 3 melanocortin receptor binding; G-protein-coupled receptor binding; type 4 melanocortin receptor binding; hormone activity; receptor binding

Biological Process: generation of precursor metabolites and energy; cell-cell signaling; neuropeptide signaling pathway; regulation of blood pressure; regulation of appetite; positive regulation of transcription from RNA polymerase II promoter; negative regulation of tumor necrosis factor production; glucose homeostasis; signal transduction; cellular pigmentation
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 Research Articles on ACTH    1. Data indicate that LIM-homeodomain transcription factor Islet 1 is necessary for hypothalamic proopiomelanocortin gene (Pomc) expression during embryogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ACTH clia kitPathways associated with ACTH clia kit
 Reference Product  PubMed Publications
 Crh clia kit  >2247 publications with ACTH and Crh
 Npy clia kit  >836 publications with ACTH and Npy
 Mc4r clia kit  >369 publications with ACTH and Mc4r
 Mc1r clia kit  >237 publications with ACTH and Mc1r
 Cyp17a1 clia kit  >202 publications with ACTH and Cyp17a1
 Mc3r clia kit  >155 publications with ACTH and Mc3r
 Mc2r clia kit  >133 publications with ACTH and Mc2r
 Mc5r clia kit  >92 publications with ACTH and Mc5r
 Pdyn clia kit  >27 publications with ACTH and Pdyn
 Nmu clia kit  >13 publications with ACTH and Nmu
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Endogenous Sterols Pathway antibodies  Endogenous Sterols Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 G-protein Activation Pathway antibodies  G-protein Activation Pathway Diagram
Organs/Tissues associated with ACTH clia kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >18646 publications with ACTH and Brain
 Pituitary Gland Antibodies  >9046 publications with ACTH and Pituitary Gland
 Skin Antibodies  >1906 publications with ACTH and Skin
 Testis Antibodies  >557 publications with ACTH and Testis
 Embryonic Tissue Antibodies  >393 publications with ACTH and Embryonic Tissue
 Uncharacterized Tissue Antibodies  >2 publications with ACTH and Uncharacterized Tissue
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