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ADCY1 clia kit :: Human ADCY1 (Adenylate Cyclase 1, Brain) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2531245
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADCY1 (Adenylate Cyclase 1, Brain), CLIA Kit

 Also Known As   

Human ADCY1 (Adenylate Cyclase 1, Brain) CLIA Kit

 Product Synonym Names    AC1
 Product Gene Name   

ADCY1 clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    103072
 3D Structure    ModBase 3D Structure for Q08828
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant ADCY1. No significant cross-reactivity or interference between ADCY1 and analogues was observed.
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 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADCY1 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ADCY1 clia kit

   Intended Uses: This CLIA kit applies to the in vitro quantitative determination of ADCY1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to ADCY1. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ADCY1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ADCY1, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of ADCY1. You can calculate the concentration of ADCY1 in the samples by comparing the RLU value of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of ADCY1 clia kit    ADCY1 clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2531245. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ADCY1. It may not necessarily be applicable to this product.
 NCBI GI #    31083193
 NCBI GeneID    107
 NCBI Accession #    NP_066939.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021116.2 [Other Products]
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 UniProt Primary Accession #    Q08828 [Other Products]
 UniProt Secondary Accession #    Q75MI1; A4D2L8 [Other Products]
 UniProt Related Accession #    Q08828 [Other Products]
 Molecular Weight    123,440 Da
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 NCBI Official Full Name    adenylate cyclase type 1 isoform 1
 NCBI Official Synonym Full Names    adenylate cyclase 1
 NCBI Official Symbol    ADCY1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    adenylate cyclase type 1
 UniProt Protein Name    Adenylate cyclase type 1
 UniProt Synonym Protein Names   
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
 Protein Family    Adenylate cyclase
 UniProt Gene Name    ADCY1 [Similar Products]
 UniProt Entry Name    ADCY1_HUMAN
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 NCBI Summary for ADCY1    This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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 UniProt Comments for ADCY1    ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Transporter; Adenylyl cyclase; Transporter, aquaporin family; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Membrane protein, integral; Lyase; EC

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; circadian rhythm; response to drug; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; response to lithium ion; activation of protein kinase A; regulation of circadian rhythm; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; cAMP-mediated signaling; axonogenesis; long-term memory; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport

Disease: Deafness, Autosomal Recessive 44
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 Research Articles on ADCY1    1. Maps to 7p14.1-q11.22 between D7S2209 and marker D7S2435, maximum Lod score 5 for D7S1818.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ADCY1 clia kitOrgans/Tissues associated with ADCY1 clia kit
 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with ADCY1 and Brain
 Eye Antibodies  >8 publications with ADCY1 and Eye
 Nerve Antibodies  >4 publications with ADCY1 and Nerve
 Embryonic Tissue Antibodies  >3 publications with ADCY1 and Embryonic Tissue
 Kidney Antibodies  >2 publications with ADCY1 and Kidney
 Pancreas Antibodies  >1 publications with ADCY1 and Pancreas
 Bone Antibodies  >1 publications with ADCY1 and Bone
 Skin Antibodies  >1 publications with ADCY1 and Skin
 Heart Antibodies  >1 publications with ADCY1 and Heart
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