AAI37097.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,878 Da
NCBI Official Full Name
Activated leukocyte cell adhesion molecule
NCBI Official Synonym Full Names
activated leukocyte cell adhesion molecule
NCBI Official Synonym Symbols
NCBI Protein Information
CD166 antigen
UniProt Protein Name
CD166 antigen
UniProt Synonym Protein Names
Activated leukocyte cell adhesion molecule; CD_antigen: CD166
UniProt Synonym Gene Names
UniProt Entry Name
CD166_HUMAN
NCBI Summary for ALCAM
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
UniProt Comments for ALCAM
ALCAM: Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 3q13.1
Cellular Component: focal adhesion; cell soma; axon; integral to membrane; external side of plasma membrane
Molecular Function: protein binding; receptor binding
Biological Process: axon guidance; motor axon guidance; signal transduction; cell adhesion
Research Articles on ALCAM
Precautions
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Disclaimer
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Products associated with ALCAM clia kit
Pathways associated with ALCAM clia kit
Organs/Tissues associated with ALCAM clia kit
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