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ALCAM clia kit :: Human Activated Leukocyte Cell Adhesion Molecule (ALCAM) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2025416 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $305 +1 FREE 8GB USB
48-Strip-Wells  /  $575 +1 FREE 8GB USB
96-Strip-Wells  /  $785 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,190 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,755 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Activated Leukocyte Cell Adhesion Molecule (ALCAM), CLIA Kit

 Also Known As   

Activated Leukocyte Cell Adhesion Molecule (ALCAM) CLIA Kit

 Product Synonym Names    CD166; MEMD; Activated Leucocyte Cell Adhesion Molecule
 Product Gene Name   

ALCAM clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    601662
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Activated Leukocyte Cell Adhesion Molecule (ALCAM).
No significant cross-reactivity or interference between Activated Leukocyte Cell Adhesion Molecule (ALCAM) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernates and Other Biological Fluids
 Detection Range    27.4-20,000pg/mL
 Sensitivity    < 12.9pg/mL
 Application    Chemiluminescent immunoassay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Activated Leukocyte Cell Adhesion Molecule (ALCAM) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Activated Leukocyte Cell Adhesion Molecule (ALCAM) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ALCAM clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ALCAM clia kit

   The microplate provided in this kit has been pre-coated with an antibody specific to Activated Leukocyte Cell Adhesion Molecule (ALCAM). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to Activated Leukocyte Cell Adhesion Molecule (ALCAM). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the Activated Leukocyte Cell Adhesion Molecule (ALCAM) level in the sample or standard.;
 Product Categories/Family for ALCAM clia kit    CD & Adhesion molecule; Tumor immunity
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 Typical Testing Data/Standard Curve (for reference only) of ALCAM clia kit    ALCAM clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2025416. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ALCAM. It may not necessarily be applicable to this product.
 NCBI GI #    187951595
 NCBI GeneID    214
 NCBI Accession #    AAI37097.1 [Other Products]
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 UniProt Secondary Accession #    O60892; Q1HGM8; Q1HGM9; Q6PEY4; Q6ZS95; B2RNS3; B4DTU0 [Other Products]
 UniProt Related Accession #    Q13740 [Other Products]
 Molecular Weight    33,878 Da
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 NCBI Official Full Name    Activated leukocyte cell adhesion molecule
 NCBI Official Synonym Full Names    activated leukocyte cell adhesion molecule
 NCBI Official Symbol    ALCAM [Similar Products]
 NCBI Official Synonym Symbols   
MEMD; CD166
[Similar Products]
 NCBI Protein Information    CD166 antigen
 UniProt Protein Name    CD166 antigen
 UniProt Synonym Protein Names   
Activated leukocyte cell adhesion molecule; CD_antigen: CD166
 Protein Family    CD166 antigen
 UniProt Gene Name    ALCAM [Similar Products]
 UniProt Synonym Gene Names    MEMD [Similar Products]
 UniProt Entry Name    CD166_HUMAN
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 NCBI Summary for ALCAM    This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
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 UniProt Comments for ALCAM    ALCAM: Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 3q13.1

Cellular Component: focal adhesion; cell soma; axon; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; receptor binding

Biological Process: axon guidance; motor axon guidance; signal transduction; cell adhesion
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 Research Articles on ALCAM    1. Differentially expressed/regulated cancer-related genes upon miR-125b expression along with the significant increase of ALCAM
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ALCAM clia kitPathways associated with ALCAM clia kit
 Reference Product  PubMed Publications
 CD6 clia kit  >64 publications with ALCAM and CD6
 NT5E clia kit  >4 publications with ALCAM and NT5E
 ITGB1 clia kit  >3 publications with ALCAM and ITGB1
 PTPRC clia kit  >2 publications with ALCAM and PTPRC
 LGALS8 clia kit  >2 publications with ALCAM and LGALS8
 NDRG2 clia kit  >2 publications with ALCAM and NDRG2
 RELA clia kit  >1 publications with ALCAM and RELA
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
Diseases associated with ALCAM clia kitOrgans/Tissues associated with ALCAM clia kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >58 publications with ALCAM and Carcinoma
 Breast Neoplasms Antibodies  >33 publications with ALCAM and Breast Neoplasms
 Adenocarcinoma Antibodies  >28 publications with ALCAM and Adenocarcinoma
 Immune System Diseases Antibodies  >25 publications with ALCAM and Immune System Diseases
 Inflammation Antibodies  >18 publications with ALCAM and Inflammation
 Lung Diseases Antibodies  >16 publications with ALCAM and Lung Diseases
 Necrosis Antibodies  >15 publications with ALCAM and Necrosis
 Prostatic Neoplasms Antibodies  >13 publications with ALCAM and Prostatic Neoplasms
 Liver Neoplasms Antibodies  >12 publications with ALCAM and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >11 publications with ALCAM and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >139 publications with ALCAM and Blood
 Bone Antibodies  >70 publications with ALCAM and Bone
 Nerve Antibodies  >64 publications with ALCAM and Nerve
 Embryonic Tissue Antibodies  >59 publications with ALCAM and Embryonic Tissue
 Brain Antibodies  >59 publications with ALCAM and Brain
 Vascular Antibodies  >48 publications with ALCAM and Vascular
 Bone Marrow Antibodies  >48 publications with ALCAM and Bone Marrow
 Lung Antibodies  >37 publications with ALCAM and Lung
 Liver Antibodies  >26 publications with ALCAM and Liver
 Eye Antibodies  >23 publications with ALCAM and Eye
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