NP_036648.2
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
62,266 Da
NCBI Official Full Name
C4b-binding protein alpha chain
NCBI Official Synonym Full Names
complement component 4 binding protein, alpha
NCBI Official Synonym Symbols
NCBI Protein Information
C4b-binding protein alpha chain
UniProt Protein Name
C4b-binding protein alpha chain
UniProt Synonym Gene Names
UniProt Entry Name
C4BPA_RAT
NCBI Summary for C4BPa
regulatory protein for the complement system of the innate immune response [RGD, Feb 2006]
UniProt Comments for C4BPa
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Research Articles on C4BPa
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Products associated with C4BPa clia kit
Pathways associated with C4BPa clia kit
Organs/Tissues associated with C4BPa clia kit
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