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CK-18/KRT18 clia kit :: Human CK-18/KRT18 (Cytokeratin 18) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2531904
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CK-18/KRT18 (Cytokeratin 18), CLIA Kit

★Popular Item★
 Also Known As   

Human CK-18/KRT18 (Cytokeratin 18) CLIA Kit

 Product Synonym Names    CYK18; K18
 Product Gene Name   

CK-18/KRT18 clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2531904 COA    COA PDF
 OMIM    148070
 3D Structure    ModBase 3D Structure for P05783
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 Species Reactivity    Human
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 Specificity    This kit recognizes Human CK-18/KRT18 in samples. No significant cross-reactivity or interference between Human CK-18/KRT18 and analogues was observed.
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 Samples    serum, plasma and other biological fluids
 Detection Range    31.25-2000 pg/mL
 Sensitivity    18.75 pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human CK-18/KRT18 were tested 20 times on one plate, respectively.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human CK-18/KRT18 were tested on 3 different plates, 20 replicates in each plate.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CK-18/KRT18 clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CK-18/KRT18 clia kit

   Intended Uses: This CLIA kit applies to the in vitro quantitative determination of Human CK-18/KRT18 concentrations in serum, plasma and other biological fluids.
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 Typical Testing Data/Standard Curve (for reference only) of CK-18/KRT18 clia kit    CK-18/KRT18 clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2531904. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CK-18/KRT18. It may not necessarily be applicable to this product.
 NCBI GI #    34037
 NCBI GeneID    3875
 NCBI Accession #    CAA31375.1 [Other Products]
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 UniProt Primary Accession #    P05783 [Other Products]
 UniProt Secondary Accession #    Q53G38; Q5U0N8; Q9BW26 [Other Products]
 UniProt Related Accession #    P05783 [Other Products]
 Molecular Weight    48,058 Da
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 NCBI Official Full Name    cytokeratin 18
 NCBI Official Synonym Full Names    keratin 18, type I
 NCBI Official Symbol    KRT18 [Similar Products]
 NCBI Official Synonym Symbols   
K18; CK-18; CYK18
[Similar Products]
 NCBI Protein Information    keratin, type I cytoskeletal 18
 UniProt Protein Name    Keratin, type I cytoskeletal 18
 UniProt Synonym Protein Names   
Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
 UniProt Gene Name    KRT18 [Similar Products]
 UniProt Synonym Gene Names    CYK18; CK-18; K18 [Similar Products]
 UniProt Entry Name    K1C18_HUMAN
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 NCBI Summary for CK-18/KRT18    KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CK-18/KRT18    K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis.

Protein type: Nucleolus; Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: perinuclear region of cytoplasm; keratin filament; cytoplasm; nucleolus; microtubule organizing center; intermediate filament

Molecular Function: protein binding; structural molecule activity

Biological Process: anatomical structure morphogenesis; viral reproduction; tumor necrosis factor-mediated signaling pathway; intermediate filament cytoskeleton organization and biogenesis; cell cycle; negative regulation of apoptosis; Golgi to plasma membrane CFTR protein transport

Disease: Cirrhosis, Familial
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 Research Articles on CK-18/KRT18    1. Under the present study design propofol or sevoflurane anaesthesia did not induce apoptosis or affected the liver function as assessed by the M30, M65 markers and liver enzymes in patients undergoing mastectomy or thyroidectomy under general anaesthesia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CK-18/KRT18 clia kitPathways associated with CK-18/KRT18 clia kit
 Reference Product  PubMed Publications
 KRT8 clia kit  >54 publications with CK-18/KRT18 and KRT8
 EGR1 clia kit  >1 publications with CK-18/KRT18 and EGR1
 TCHP clia kit  >1 publications with CK-18/KRT18 and TCHP
 CASP6 clia kit  >1 publications with CK-18/KRT18 and CASP6
 Products by Pathway  Pathway Diagram
 Caspase Cascade In Apoptosis Pathway antibodies  Caspase Cascade In Apoptosis Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
Organs/Tissues associated with CK-18/KRT18 clia kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >50 publications with CK-18/KRT18 and Liver
 Blood Antibodies  >30 publications with CK-18/KRT18 and Blood
 Prostate Antibodies  >9 publications with CK-18/KRT18 and Prostate
 Lymph Antibodies  >8 publications with CK-18/KRT18 and Lymph
 Lymph Node Antibodies  >8 publications with CK-18/KRT18 and Lymph Node
 Muscle Antibodies  >7 publications with CK-18/KRT18 and Muscle
 Kidney Antibodies  >7 publications with CK-18/KRT18 and Kidney
 Stomach Antibodies  >7 publications with CK-18/KRT18 and Stomach
 Eye Antibodies  >6 publications with CK-18/KRT18 and Eye
 Bone Antibodies  >5 publications with CK-18/KRT18 and Bone
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