View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List C1r clia kit :: Human Complement Component 1, R Subcomponent (C1r) CLIA Kit Catalog # MBS2000876 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment) Unit / Price 24-Strip-Wells / $415 +1 FREE 8GB USB 48-Strip-Wells / $635 +1 FREE 8GB USB 96-Strip-Wells / $855 +1 FREE 8GB USB 5x96-Strip-Wells / $3,445 +4 FREE 8GB USB 10x96-Strip-Wells / $6,300 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Complement Component 1, R Subcomponent (C1r), CLIA Kit Full Product Name Human Complement Component 1, R Subcomponent (C1r) CLIA Kit Product Synonym Names C1-r; complement Component 1; Complement component 1 subcomponent r Product Gene Name C1r clia kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual OMIM 216950 3D Structure ModBase 3D Structure for P00736 Species Reactivity Human Specificity This assay has high sensitivity and excellent specificity for detection of Complement Component 1, R Subcomponent (C1r). No significant cross-reactivity or interference between Complement Component 1, R Subcomponent (C1r) and analogues was observed. Assay Type Double-antibody Sandwich Samples Serum, Plasma and other biological fluids Detection Range 0.41-300ng/mL Sensitivity 0.14ng/mL Application Chemiluminescent immunoassay for Antigen Detection. Intra-assay Precision (Precision within an assay) 3 samples with low, middle and high level Complement Component 1, R Subcomponent (C1r) were tested 20 times on one plate, respectively. Inter-assay Precision (Precision between assays) 3 samples with low, middle and high level Complement Component 1, R Subcomponent (C1r) were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100 Intra-Assay CV<10% Inter-Assay CV<12% Preparation and Storage The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end. ISO Certification Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of C1r clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for C1r clia kit The microplate provided in this kit has been pre-coated with an antibody specific to Complement Component 1, R Subcomponent (C1r). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to Complement Component 1, R Subcomponent (C1r). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the Complement Component 1, R Subcomponent (C1r) level in the sample or standard.; Product Categories/Family for C1r clia kit Signal transduction; Infection immunity; Immune molecule Typical Testing Data/Standard Curve (for reference only) of C1r clia kit TOP Sample Manual Insert of MBS2000876. NCBI/Uniprot data below describe general gene information for C1r. It may not necessarily be applicable to this product. NCBI GI # 23243256 NCBI GeneID 715 NCBI Accession # AAH35220.1 [Other Products] UniProt Primary Accession # P00736 [Other Products] UniProt Secondary Accession # Q68D77; Q8J012; A6NJQ8[Other Products] UniProt Related Accession # P00736[Other Products] Molecular Weight 80,119 Da TOP NCBI Official Full Name Complement component 1, r subcomponent NCBI Official Synonym Full Names complement component 1, r subcomponent NCBI Official Symbol C1R [Similar Products] NCBI Protein Information complement C1r subcomponent UniProt Protein Name Complement C1r subcomponent UniProt Synonym Protein Names Complement component 1 subcomponent r Protein Family Complement C1r subcomponent UniProt Gene Name C1R [Similar Products] UniProt Entry Name C1R_HUMAN TOP TOP UniProt Comments for C1r C1R: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. Belongs to the peptidase S1 family.Protein type: Protease; EC 3.4.21.41Chromosomal Location of Human Ortholog: 12p13Cellular Component: extracellular regionMolecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity; calcium ion bindingBiological Process: innate immune response; immune response; proteolysis; complement activation, classical pathway; complement activationDisease: Complement Component C1r/c1s Deficiency Research Articles on C1r 1. C1r specificity is well suited to its cleavage targets and that efficient cleavage of C1s is achieved through both active site and exosite contributions. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with C1r clia kit Reference Product PubMed Publications C1S clia kit >587 publications with C1r and C1S CRP clia kit >10 publications with C1r and CRP SERPING1 clia kit >7 publications with C1r and SERPING1 C1QB clia kit >6 publications with C1r and C1QB C1QC clia kit >3 publications with C1r and C1QC C1QA clia kit >3 publications with C1r and C1QA Pathways associated with C1r clia kit Products by Pathway Pathway Diagram Classical Antibody-mediated Complement Activation Pathway antibodies Classical Antibody-mediated Complement Activation Pathway Diagram Complement Activation, Classical Pathway antibodies Complement Activation, Classical Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement Cascade Pathway antibodies Complement Cascade Pathway Diagram Creation Of C4 And C2 Activators Pathway antibodies Creation Of C4 And C2 Activators Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Initial Triggering Of Complement Pathway antibodies Initial Triggering Of Complement Pathway Diagram Innate Immune System Pathway antibodies Innate Immune System Pathway Diagram Diseases associated with C1r clia kit Disease Name Pubmed Publications COMPLEMENT COMPONENT C1r/C1s DEFICIENCY Antibodies >62 publications with C1r and COMPLEMENT COMPONENT C1r/C1s DEFICIENCY Cardiovascular Diseases Antibodies >52 publications with C1r and Cardiovascular Diseases Neoplasms Antibodies >50 publications with C1r and Neoplasms Inflammation Antibodies >43 publications with C1r and Inflammation Kidney Diseases Antibodies >18 publications with C1r and Kidney Diseases Necrosis Antibodies >18 publications with C1r and Necrosis Brain Diseases Antibodies >18 publications with C1r and Brain Diseases Liver Diseases Antibodies >15 publications with C1r and Liver Diseases Edema Antibodies >13 publications with C1r and Edema Disease Models, Animal Antibodies >10 publications with C1r and Disease Models, Animal Organs/Tissues associated with C1r clia kit Organ/Tissue Name Pubmed Publications Blood Antibodies >242 publications with C1r and Blood Bone Antibodies >53 publications with C1r and Bone Liver Antibodies >41 publications with C1r and Liver Skin Antibodies >31 publications with C1r and Skin Vascular Antibodies >30 publications with C1r and Vascular Brain Antibodies >28 publications with C1r and Brain Kidney Antibodies >25 publications with C1r and Kidney Embryonic Tissue Antibodies >24 publications with C1r and Embryonic Tissue Lung Antibodies >19 publications with C1r and Lung Muscle Antibodies >17 publications with C1r and Muscle TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers Major outer membrane porin, serovar C (ompA) Recombinant Protein IgG Secondary Antibody CRY1 Antibody Calcium-calmodulin dependent protein kinase type II subunit ... ELISA Kit Equol ELISA Kit IgG Antibody Sodium-Iodide Symporter (SLC5A5) Antibody CNNM2 Antibody ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments