NP_000907.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,772 Da
NCBI Official Full Name
oxytocin receptor
NCBI Official Synonym Full Names
oxytocin receptor
NCBI Official Synonym Symbols
NCBI Protein Information
oxytocin receptor
UniProt Protein Name
Oxytocin receptor
UniProt Synonym Gene Names
UniProt Entry Name
OXYR_HUMAN
NCBI Summary for OTR
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
UniProt Comments for OTR
OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 3p25
Cellular Component: microvillus; cell-cell adherens junction; integral to plasma membrane; apical plasma membrane; plasma membrane; cytosol
Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity
Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; eating behavior; maternal behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; positive regulation of synaptogenesis; G-protein coupled receptor protein signaling pathway; telencephalon development; gut development; suckling behavior; regulation of systemic arterial blood pressure by vasopressin; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
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Products associated with OTR clia kit
Pathways associated with OTR clia kit
Organs/Tissues associated with OTR clia kit
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