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PDGFRL clia kit :: Mouse PDGFRL (Platelet Derived Growth Factor Receptor Like Protein) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2532493
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PDGFRL (Platelet Derived Growth Factor Receptor Like Protein), CLIA Kit

 Also Known As   

Mouse PDGFRL (Platelet Derived Growth Factor Receptor Like Protein) CLIA Kit

 Product Synonym Names    PRLTS; PDGF-Receptor Beta-Like Tumor Suppressor
 Product Gene Name   

PDGFRL clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    114500
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 Species Reactivity    Mouse
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 Specificity    This kit recognizes natural and recombinant PDGFRL. No significant cross-reactivity or interference between PDGFRL and analogues was observed.
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 Assay Type    Sandwich
 Detection Range    15.625-1000pg/mL
 Sensitivity    Min: 9.375pg/mL; Max: 1000pg/mL
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDGFRL clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PDGFRL clia kit

   Intended Uses: This CLIA kit applies to the in vitro quantitative determination of PDGFRL concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to PDGFRL. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PDGFRL and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PDGFRL, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of PDGFRL. You can calculate the concentration of PDGFRL in the samples by comparing the RLU value of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of PDGFRL clia kit    PDGFRL clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2532493. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PDGFRL. It may not necessarily be applicable to this product.
 NCBI GI #    5453872
 NCBI GeneID    5157
 NCBI Accession #    NP_006198.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006207.2 [Other Products]
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 UniProt Secondary Accession #    Q6FH04; A8K085 [Other Products]
 UniProt Related Accession #    Q15198 [Other Products]
 Molecular Weight    41,861 Da
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 NCBI Official Full Name    platelet-derived growth factor receptor-like protein
 NCBI Official Synonym Full Names    platelet-derived growth factor receptor-like
 NCBI Official Symbol    PDGFRL [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    platelet-derived growth factor receptor-like protein
 UniProt Protein Name    Platelet-derived growth factor receptor-like protein
 UniProt Synonym Protein Names   
PDGF receptor beta-like tumor suppressor
 Protein Family    Platelet-derived growth factor receptor-like protein
 UniProt Gene Name    PDGFRL [Similar Products]
 UniProt Synonym Gene Names    PRLTS; PDGFR-like protein [Similar Products]
 UniProt Entry Name    PGFRL_HUMAN
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 NCBI Summary for PDGFRL    This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PDGFRL    PDGFRL: Defects in PDGFRL are associated with colorectal cancer (CRC).

Protein type: Secreted; Receptor, misc.; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p22-p21.3

Cellular Component: extracellular region

Molecular Function: platelet activating factor receptor activity; platelet-derived growth factor beta-receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Disease: Hepatocellular Carcinoma
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 Research Articles on PDGFRL    1. review elucidates the role of tumor stroma interactions, the roles of PDGF receptor signaling in cancer-associated fibroblasts via alteration of stromal matrix composition and the mitogenic effects of cancer-derived PDGFs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with PDGFRL clia kit
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >2 publications with PDGFRL and Ovary
 Eye Antibodies  >1 publications with PDGFRL and Eye
 Brain Antibodies  >1 publications with PDGFRL and Brain
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