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TSH clia kit :: Rat TSH (Thyroid Stimulating Hormone) CLIA Kit

Scan QR to view Datasheet Catalog #    MBS2532012
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TSH (Thyroid Stimulating Hormone), CLIA Kit

★Popular Item★
 Also Known As   

Rat TSH (Thyroid Stimulating Hormone) CLIA Kit

 Product Synonym Names    Thyrotropin
 Product Gene Name   

TSH clia kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    118850
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 Species Reactivity    Rat
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 Specificity    This kit recognizes natural and recombinant TSH. No significant cross-reactivity or interference between TSH and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    0.188ng/mL
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our CLIA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TSH clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TSH clia kit

   Intended Uses: This CLIA kit applies to the in vitro quantitative determination of TSH concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to TSH. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for TSH and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain TSH, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of TSH. You can calculate the concentration of TSH in the samples by comparing the RLU value of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of TSH clia kit    TSH clia kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2532012. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TSH. It may not necessarily be applicable to this product.
 NCBI GI #    546845
 NCBI GeneID    1081
 NCBI Accession #    AAB30827.1 [Other Products]
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 UniProt Related Accession #    P01215 [Other Products]
 Molecular Weight    13,075 Da
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 NCBI Official Full Name    thyroid-stimulating hormone alpha subunit
 NCBI Official Synonym Full Names    glycoprotein hormones, alpha polypeptide
 NCBI Official Symbol    CGA [Similar Products]
 NCBI Official Synonym Symbols   
HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA
[Similar Products]
 NCBI Protein Information    glycoprotein hormones alpha chain
 UniProt Protein Name    Glycoprotein hormones alpha chain
 UniProt Synonym Protein Names   
Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
 Protein Family    Temperature-sensitive hemagglutinin tsh autotransporter
 UniProt Gene Name    CGA [Similar Products]
 UniProt Synonym Gene Names    CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha [Similar Products]
 UniProt Entry Name    GLHA_HUMAN
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 NCBI Summary for TSH    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for TSH    CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6q12-q21

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; peptide hormone processing; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration
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 Research Articles on TSH    1. A single low TSH at baseline was associated with increased risk of hip fractures (adj HR 1.16, 95% CI 1.07-1.26, p < 0.001) but not major osteoporotic fractures (MOF, adj HR 1.06, 95% CI 0.99-1.12, p = 0.058) over a median follow-up of 7.5 years.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TSH clia kitPathways associated with TSH clia kit
 Reference Product  PubMed Publications
 LHB clia kit  >31 publications with TSH and LHB
 FSHB clia kit  >29 publications with TSH and FSHB
 POMC clia kit  >20 publications with TSH and POMC
 TSHB clia kit  >8 publications with TSH and TSHB
 FSHR clia kit  >6 publications with TSH and FSHR
 LHCGR clia kit  >3 publications with TSH and LHCGR
 CGB5 clia kit  >1 publications with TSH and CGB5
 CGB8 clia kit  >1 publications with TSH and CGB8
 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 FSH Signaling Pathway antibodies  FSH Signaling Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
Organs/Tissues associated with TSH clia kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >179 publications with TSH and Brain
 Lung Antibodies  >168 publications with TSH and Lung
 Liver Antibodies  >148 publications with TSH and Liver
 Stomach Antibodies  >142 publications with TSH and Stomach
 Thyroid Antibodies  >111 publications with TSH and Thyroid
 Heart Antibodies  >109 publications with TSH and Heart
 Vascular Antibodies  >104 publications with TSH and Vascular
 Muscle Antibodies  >103 publications with TSH and Muscle
 Pituitary Gland Antibodies  >77 publications with TSH and Pituitary Gland
 Skin Antibodies  >60 publications with TSH and Skin
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