NP_115743.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
25,132 Da
NCBI Official Full Name
zinc finger BED domain-containing protein 3
NCBI Official Synonym Full Names
zinc finger, BED-type containing 3
NCBI Protein Information
zinc finger BED domain-containing protein 3
UniProt Protein Name
Zinc finger BED domain-containing protein 3
UniProt Synonym Protein Names
Axin-interacting protein
UniProt Entry Name
ZBED3_HUMAN
UniProt Comments for ZBED3
ZBED3: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression. Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 5q13.3
Cellular Component: membrane; cytosol
Molecular Function: DNA binding; metal ion binding
Biological Process: Wnt receptor signaling pathway; protein stabilization; negative regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on ZBED3
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Products associated with ZBED3 clia kit
Organs/Tissues associated with ZBED3 clia kit
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