NP_058917.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
47,630 Da
NCBI Official Full Name
sonic hedgehog protein
NCBI Official Synonym Full Names
sonic hedgehog
NCBI Protein Information
sonic hedgehog protein
UniProt Protein Name
Sonic hedgehog protein
UniProt Synonym Gene Names
NCBI Summary for SHH
plays a role in neurogenesis; regulates proliferation of adult hippocampal neural stem cells [RGD, Feb 2006]
UniProt Comments for SHH
Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO ().
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Products associated with SHH diy elisa kit
Pathways associated with SHH diy elisa kit
Diseases associated with SHH diy elisa kit
Organs/Tissues associated with SHH diy elisa kit
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