View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List BMP-2 elisa kit Catalog # MBS1751022 Unit / Price 96-Strip-Wells / $510 +1 FREE 8GB USB 5x96-Strip-Wells / $2,305 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name BMP-2, ELISA Kit Full Product Name Bovine BMP-2 PicoKine ELISA Kit Product Synonym Names Bone morphogenetic protein 2; BMP2 Product Gene Name BMP-2 elisa kit[Similar Products] Product Synonym Gene Name BMP2[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual 3D Structure ModBase 3D Structure for C8C060 Species Reactivity BovineThere is no detectable cross-reactivity with other relevant proteins. Specificity Natural and recombinant Bovine Bovine BMP-2 Assay Type Quantitative Sandwich Detection Range 31.2pg/ml-2000pg/ml Sensitivity <2pg/ml Intra-assay Precision Intra-Assay Precision (Precision within an assay) Three samples of known concentration weretested on one plate to assess intra-assay precision Inter-assay Precision Inter-Assay Precision (Precision between assays) Three samples of known concentration weretested in separate assays to assess inter-assay precision. Preparation and Storage Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles. Production Time Due to severe delay and raw materials shortage, production time may takes between 5-8 weeks. ISO Certification Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of BMP-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for BMP-2 purchase MBS1751022 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BMP-2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing BMP-2. The ELISA analytical biochemical technique of the MBS1751022 kit is based on BMP-2 antibody-BMP-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for BMP-2 elisa kit Principle of the Assay: Bovine Bovine BMP-2 ELISA Kit was based on standard sandwich enzyme-linked immune- sorbent assay technology. A monoclonal antibody from mouse specific for Bovine BMP-2 has been precoated onto 96-well plates. Standards(Expression system for standard: CHO; Immunogen sequence: Q283-R396) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Bovine BMP-2 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Bovine Bovine BMP-2 amount of sample captured in plate.Background: Bone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF- beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant Bovine BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa. Product Categories/Family for BMP-2 elisa kit Cardiovascular; Angiogenesis; Growth Factors; TGF; Signal Transduction; Growth Factors/Hormones; Cytoskeleton/ECM; Extracellular Matrix; Structures; Bone; Stem Cells; Signaling Pathways; TGF Beta; Secreted; Neural Stem Cells; Extracellular; Cancer Applications Tested/Suitable for BMP-2 elisa kit ELISA (EIA) Typical Testing Data/Standard Curve (for reference only) of BMP-2 elisa kit TOP Sample Manual Insert of MBS1751022. NCBI/Uniprot data below describe general gene information for BMP-2. It may not necessarily be applicable to this product. NCBI GI # 4557369 NCBI GeneID 650 NCBI Accession # NP_001191.1 [Other Products] NCBI GenBank Nucleotide # NM_001200.3 [Other Products] UniProt Primary Accession # C8C060 [Other Products] UniProt Related Accession # P12643[Other Products] Molecular Weight 44702 MW TOP NCBI Official Full Name bone morphogenetic protein 2 preproprotein NCBI Official Synonym Full Names bone morphogenetic protein 2 NCBI Official Symbol BMP2 [Similar Products] NCBI Official Synonym Symbols BDA2; BMP2A [Similar Products] NCBI Protein Information bone morphogenetic protein 2 UniProt Protein Name Bone morphogenetic protein 2 UniProt Synonym Protein Names Bone morphogenetic protein 2 Protein Family BMP-2-inducible protein kinase UniProt Gene Name BMP2 [Similar Products] TOP NCBI Summary for BMP-2 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] TOP Research Articles on BMP-2 1. these results suggest that the BMP2 gene polymorphism may be related to the development of allograft rejection and graft dysfunction in kidney transplant recipients TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with BMP-2 elisa kit Reference Product PubMed Publications BMPR2 elisa kit >207 publications with BMP-2 and BMPR2 BMPR1A elisa kit >180 publications with BMP-2 and BMPR1A SMAD4 elisa kit >96 publications with BMP-2 and SMAD4 BMPR1B elisa kit >60 publications with BMP-2 and BMPR1B SMAD7 elisa kit >34 publications with BMP-2 and SMAD7 NOG elisa kit >11 publications with BMP-2 and NOG ACVR2B elisa kit >9 publications with BMP-2 and ACVR2B GREM2 elisa kit >8 publications with BMP-2 and GREM2 CHRD elisa kit >3 publications with BMP-2 and CHRD SOSTDC1 elisa kit >2 publications with BMP-2 and SOSTDC1 Pathways associated with BMP-2 elisa kit Products by Pathway Pathway Diagram Adipogenesis Pathway antibodies Adipogenesis Pathway Diagram BDNF Signaling Pathway antibodies BDNF Signaling Pathway Diagram BMP Signaling Pathway antibodies BMP Signaling Pathway Diagram BMP Signaling Pathway antibodies BMP Signaling Pathway Diagram BMP Signalling And Regulation Pathway antibodies BMP Signalling And Regulation Pathway Diagram Basal Cell Carcinoma Pathway antibodies Basal Cell Carcinoma Pathway Diagram Basal Cell Carcinoma Pathway antibodies Basal Cell Carcinoma Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Elastic Fibre Formation Pathway antibodies Elastic Fibre Formation Pathway Diagram Diseases associated with BMP-2 elisa kit Disease Name Pubmed Publications Bone Diseases Antibodies >571 publications with BMP-2 and Bone Diseases Necrosis Antibodies >113 publications with BMP-2 and Necrosis Inflammation Antibodies >93 publications with BMP-2 and Inflammation Pain Antibodies >46 publications with BMP-2 and Pain Hypertrophy Antibodies >45 publications with BMP-2 and Hypertrophy Hypertension Antibodies >44 publications with BMP-2 and Hypertension Fibrosis Antibodies >34 publications with BMP-2 and Fibrosis Breast Neoplasms Antibodies >33 publications with BMP-2 and Breast Neoplasms Adenocarcinoma Antibodies >32 publications with BMP-2 and Adenocarcinoma Kidney Diseases Antibodies >32 publications with BMP-2 and Kidney Diseases Organs/Tissues associated with BMP-2 elisa kit Organ/Tissue Name Pubmed Publications Bone Antibodies >4206 publications with BMP-2 and Bone Connective Tissue Antibodies >649 publications with BMP-2 and Connective Tissue Embryonic Tissue Antibodies >456 publications with BMP-2 and Embryonic Tissue Heart Antibodies >192 publications with BMP-2 and Heart Brain Antibodies >163 publications with BMP-2 and Brain Kidney Antibodies >95 publications with BMP-2 and Kidney Lung Antibodies >83 publications with BMP-2 and Lung Liver Antibodies >70 publications with BMP-2 and Liver Eye Antibodies >63 publications with BMP-2 and Eye Uterus Antibodies >30 publications with BMP-2 and Uterus TOP © 2006-24 MyBioSource.com. 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