NM_201635.3
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,448 Da
NCBI Official Full Name
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
NCBI Official Synonym Full Names
cytochrome P450, family 24, subfamily a, polypeptide 1
NCBI Official Synonym Symbols
Cyp24; VITD12; 24-OHase; 24R-Ohase; P450-CC24 [Similar Products]
NCBI Protein Information
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
UniProt Protein Name
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
UniProt Synonym Protein Names
Cytochrome P450 24A1; Cytochrome P450-CC24
UniProt Synonym Gene Names
UniProt Entry Name
CP24A_RAT
NCBI Summary for 1,25 (OH)2D3
enzyme involved in vitamin D metabolism; linked to albuminuria, hyperlipidemia and atherosclerotic aorta lesions [RGD, Feb 2006]
UniProt Comments for 1,25 (OH)2D3
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid.
Research Articles on 1,25 (OH)2D3
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Disclaimer
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Products associated with 1,25 (OH)2D3 elisa kit
Pathways associated with 1,25 (OH)2D3 elisa kit
Diseases associated with 1,25 (OH)2D3 elisa kit
Disease Name |
Pubmed Publications |
Kidney Diseases Antibodies |
>119 publications with 1,25 (OH)2D3 and Kidney Diseases |
Hypercalcemia Antibodies |
>94 publications with 1,25 (OH)2D3 and Hypercalcemia |
Prostatic Neoplasms Antibodies |
>67 publications with 1,25 (OH)2D3 and Prostatic Neoplasms |
Breast Neoplasms Antibodies |
>62 publications with 1,25 (OH)2D3 and Breast Neoplasms |
Inflammation Antibodies |
>41 publications with 1,25 (OH)2D3 and Inflammation |
Renal Insufficiency Antibodies |
>39 publications with 1,25 (OH)2D3 and Renal Insufficiency |
Disease Models, Animal Antibodies |
>37 publications with 1,25 (OH)2D3 and Disease Models, Animal |
Hypercalciuria Antibodies |
>34 publications with 1,25 (OH)2D3 and Hypercalciuria |
Osteoporosis Antibodies |
>31 publications with 1,25 (OH)2D3 and Osteoporosis |
Nervous System Diseases Antibodies |
>26 publications with 1,25 (OH)2D3 and Nervous System Diseases |
Organs/Tissues associated with 1,25 (OH)2D3 elisa kit
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