NM_032741.4
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,717 Da
NCBI Official Full Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
NCBI Official Synonym Full Names
1-acylglycerol-3-phosphate O-acyltransferase 1
NCBI Official Synonym Symbols
G15; LPAATA; 1-AGPAT1; LPAAT-alpha [Similar Products]
NCBI Protein Information
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
UniProt Protein Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15
UniProt Synonym Gene Names
UniProt Entry Name
PLCA_HUMAN
NCBI Summary for AGPAT1
This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for AGPAT1
AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Protein type: EC 2.3.1.51; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane
Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; protein binding
Biological Process: phosphatidic acid biosynthetic process; phospholipid metabolic process; positive regulation of cellular metabolic process; positive regulation of cytokine and chemokine mediated signaling pathway; positive regulation of cytokine production; triacylglycerol biosynthetic process
Research Articles on AGPAT1
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Pathways associated with AGPAT1 elisa kit
Diseases associated with AGPAT1 elisa kit
Organs/Tissues associated with AGPAT1 elisa kit
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