NM_001316314.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
131,205 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform 1
NCBI Official Synonym Full Names
phospholipase C beta 3
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
UniProt Synonym Gene Names
UniProt Entry Name
PLCB3_HUMAN
NCBI Summary for PLCB3
This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
UniProt Comments for PLCB3
PLCB3: a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11; Phospholipase
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: cell-cell adherens junction; cytosol; nucleoplasm; protein complex
Molecular Function: calmodulin binding; phosphoinositide phospholipase C activity; phospholipase C activity
Biological Process: inositol phosphate metabolic process; regulation of systemic arterial blood pressure; Wnt receptor signaling pathway, calcium modulating pathway
Research Articles on PLCB3
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Products associated with PLCB3 elisa kit
Pathways associated with PLCB3 elisa kit
Diseases associated with PLCB3 elisa kit
Organs/Tissues associated with PLCB3 elisa kit
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