NP_055629.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51,923 Da
NCBI Official Full Name
26S proteasome non-ATPase regulatory subunit 6 isoform 2
NCBI Official Synonym Full Names
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
NCBI Official Synonym Symbols
S10; Rpn7; p42A; p44S10; SGA-113M [Similar Products]
NCBI Protein Information
26S proteasome non-ATPase regulatory subunit 6; breast cancer-associated protein SGA-113M; phosphonoformate immuno-associated protein 4; proteasome regulatory particle subunit p44S10
UniProt Protein Name
26S proteasome non-ATPase regulatory subunit 6
UniProt Synonym Protein Names
26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42A
UniProt Synonym Gene Names
UniProt Entry Name
PSMD6_HUMAN
NCBI Summary for PSMD6
This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]
UniProt Comments for PSMD6
PSMD6: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the proteasome subunit S10 family.
Chromosomal Location of Human Ortholog: 3p14.1
Cellular Component: proteasome complex; nucleoplasm; proteasome regulatory particle; cytosol
Molecular Function: ATPase activity
Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; proteolysis; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis; G1/S transition of mitotic cell cycle
Research Articles on PSMD6
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Pathways associated with PSMD6 elisa kit
Diseases associated with PSMD6 elisa kit
Organs/Tissues associated with PSMD6 elisa kit
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