NP_054769.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,661 Da
NCBI Official Full Name
39S ribosomal protein L42, mitochondrial
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L42
NCBI Official Synonym Symbols
L31MT; L42MT; S32MT; MRPL31; MRPS32; PTD007; RPML31; HSPC204; MRP-L31; MRP-L42; MRP-S32 [Similar Products]
NCBI Protein Information
39S ribosomal protein L42, mitochondrial; 28S ribosomal protein S32, mitochondrial; 39S ribosomal protein L31, mitochondrial
UniProt Protein Name
39S ribosomal protein L42, mitochondrial
UniProt Synonym Protein Names
28S ribosomal protein S32, mitochondrial; MRP-S32; S32mt; 39S ribosomal protein L31, mitochondrial; L31mt; MRP-L31
UniProt Synonym Gene Names
MRPL31; MRPS32; RPML31; HSPC204; PTD007; L42mt; MRP-L42; MRP-S32; S32mt; L31mt; MRP-L31 [Similar Products]
UniProt Entry Name
RM42_HUMAN
NCBI Summary for MRPL42
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q. [provided by RefSeq, May 2011]
UniProt Comments for MRPL42
MRPL42: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins. Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
Protein type: Ribosomal; Mitochondrial
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membrane; plasma membrane
Molecular Function: structural constituent of ribosome
Biological Process: mitochondrial translation; translation; organelle organization and biogenesis
Research Articles on MRPL42
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