NP_000687.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,802 Da
NCBI Official Full Name
4-trimethylaminobutyraldehyde dehydrogenase
NCBI Official Synonym Full Names
aldehyde dehydrogenase 9 family, member A1
NCBI Official Synonym Symbols
E3; ALDH4; ALDH7; ALDH9; TMABADH [Similar Products]
NCBI Protein Information
4-trimethylaminobutyraldehyde dehydrogenase; aldehyde dehydrogenase (NAD+); aldehyde dehydrogenase E3 isozyme; R-aminobutyraldehyde dehydrogenase; gamma-aminobutyraldehyde dehydrogenase; aldehyde dehydrogenase family 9 member A1
UniProt Protein Name
4-trimethylaminobutyraldehyde dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1 (EC:1.2.1.3); Gamma-aminobutyraldehyde dehydrogenase (EC:1.2.1.19); R-aminobutyraldehyde dehydrogenase
UniProt Synonym Gene Names
UniProt Entry Name
AL9A1_HUMAN
NCBI Summary for ALDH9A1
This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]
UniProt Comments for ALDH9A1
ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family.
Protein type: Lipid Metabolism - fatty acid; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - butanoate; EC 1.2.1.3; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - tryptophan; Mitochondrial; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - pyruvate; EC 1.2.1.47; Carbohydrate Metabolism - propanoate; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - glycerolipid; Oxidoreductase; Amino Acid Metabolism - valine, leucine and isoleucine degradation
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: mitochondrion; cytoplasm; cytosol
Molecular Function: 1-pyrroline dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; amine binding; protein homodimerization activity; aminobutyraldehyde dehydrogenase activity; 3-chloroallyl aldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; NAD binding
Biological Process: hormone metabolic process; aldehyde metabolic process; liver development; kidney development; carnitine biosynthetic process; neurotransmitter biosynthetic process
Research Articles on ALDH9A1
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Products associated with ALDH9A1 elisa kit
Pathways associated with ALDH9A1 elisa kit
Diseases associated with ALDH9A1 elisa kit
Organs/Tissues associated with ALDH9A1 elisa kit
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