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AKAP9 elisa kit :: Bovine A-kinase anchor protein 9 (AKAP9) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7207831 AKAP9 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A-kinase anchor protein 9 (AKAP9), ELISA Kit

 Also Known As   

Bovine A-kinase anchor protein 9 (AKAP9) ELISA Kit

 Product Gene Name   

AKAP9 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 611820
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 Species Reactivity    Bovine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AKAP9 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AKAP9 purchase    MBS7207831 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A-kinase anchor protein 9 (AKAP9) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AKAP9. The ELISA analytical biochemical technique of the MBS7207831 kit is based on AKAP9 antibody-AKAP9 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AKAP9 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AKAP9. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for AKAP9 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for AKAP9. It may not necessarily be applicable to this product.
 NCBI GI #    14194461
 NCBI GeneID    10142
 NCBI Accession #    Q99996.3 [Other Products]
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 UniProt Secondary Accession #    O14869; O43355; O94895; Q75N20; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2; A4D1F0; A4D1F2; A4D1F4 [Other Products]
 UniProt Related Accession #    Q99996 [Other Products]
 Molecular Weight    455,423 Da
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 NCBI Official Full Name    A-kinase anchor protein 9
 NCBI Official Synonym Full Names    A kinase (PRKA) anchor protein 9
 NCBI Official Symbol    AKAP9 [Similar Products]
 NCBI Official Synonym Symbols   
LQT11; PRKA9; AKAP-9; CG-NAP; YOTIAO; AKAP350; AKAP450; PPP1R45; HYPERION; MU-RMS-40.16A
[Similar Products]
 NCBI Protein Information    A-kinase anchor protein 9; protein yotiao; protein hyperion; AKAP 120-like protein; AKAP9-BRAF fusion protein; kinase N-associated protein; A-kinase anchor protein 350 kDa; A-kinase anchor protein 450 kDa; protein kinase A anchoring protein 9; A kinase (PRKA) anchor protein (yotiao) 9; protein phosphatase 1, regulatory subunit 45; centrosome- and Golgi-localized PKN-associated protein; centrosome- and golgi-localized protein kinase N-associated protein
 UniProt Protein Name    A-kinase anchor protein 9
 UniProt Synonym Protein Names   
A-kinase anchor protein 350 kDa; AKAP 350; hgAKAP 350; A-kinase anchor protein 450 kDa; AKAP 450; AKAP 120-like protein; Centrosome- and Golgi-localized PKN-associated protein; CG-NAP; Protein hyperion; Protein kinase A-anchoring protein 9; PRKA9; Protein yotiao
 Protein Family    A-kinase anchor protein
 UniProt Gene Name    AKAP9 [Similar Products]
 UniProt Synonym Gene Names    AKAP350; AKAP450; KIAA0803; AKAP-9; AKAP 350; hgAKAP 350; AKAP 450; CG-NAP; PRKA9 [Similar Products]
 UniProt Entry Name    AKAP9_HUMAN
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 NCBI Summary for AKAP9    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]
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 UniProt Comments for AKAP9    AKAP9: Binds to type II regulatory subunits of protein kinase A. Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. May be required to maintain the integrity of the Golgi apparatus. Isoform 4 is associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations. Defects in AKAP9 are the cause of long QT syndrome type 11 (LQT11). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: Golgi apparatus; centrosome; voltage-gated potassium channel complex; pericentriolar material; cytoskeleton; intracellular membrane-bound organelle; cytosol

Molecular Function: protein binding; potassium channel regulator activity; protein complex scaffold; receptor binding

Biological Process: synaptic transmission; transport; organelle organization and biogenesis; spermatogenesis; mitotic cell cycle; signal transduction; G2/M transition of mitotic cell cycle; positive regulation of peptidyl-serine phosphorylation; Sertoli cell development

Disease: Long Qt Syndrome 11
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 Research Articles on AKAP9    1. AKAP proteins, most likely AKAP9, maintain the bronchial epithelial barrier by regulating the E-cadherin expression at the cell membrane.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AKAP9 elisa kitDiseases associated with AKAP9 elisa kit
 Products by Pathway  Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 CREB Phosphorylation Through The Activation Of CaMKII Pathway antibodies  CREB Phosphorylation Through The Activation Of CaMKII Pathway Diagram
 CREB Phosphorylation Through The Activation Of Ras Pathway antibodies  CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 G Protein Signaling Pathways antibodies  G Protein Signaling Pathways Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Loss Of Nlp From Mitotic Centrosomes Pathway antibodies  Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
 Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway antibodies  Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >13 publications with AKAP9 and Cardiovascular Diseases
 Heart Defects, Congenital Antibodies  >12 publications with AKAP9 and Heart Defects, Congenital
 Carcinoma Antibodies  >9 publications with AKAP9 and Carcinoma
 Death Antibodies  >8 publications with AKAP9 and Death
 Skin Diseases Antibodies  >4 publications with AKAP9 and Skin Diseases
 Breast Neoplasms Antibodies  >3 publications with AKAP9 and Breast Neoplasms
 Fibrosis Antibodies  >2 publications with AKAP9 and Fibrosis
 Nervous System Diseases Antibodies  >2 publications with AKAP9 and Nervous System Diseases
 Adenocarcinoma Antibodies  >2 publications with AKAP9 and Adenocarcinoma
 Carcinoma, Squamous Cell Antibodies  >2 publications with AKAP9 and Carcinoma, Squamous Cell
Organs/Tissues associated with AKAP9 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >20 publications with AKAP9 and Heart
 Brain Antibodies  >14 publications with AKAP9 and Brain
 Muscle Antibodies  >12 publications with AKAP9 and Muscle
 Thyroid Antibodies  >10 publications with AKAP9 and Thyroid
 Blood Antibodies  >8 publications with AKAP9 and Blood
 Lung Antibodies  >7 publications with AKAP9 and Lung
 Nerve Antibodies  >3 publications with AKAP9 and Nerve
 Kidney Antibodies  >2 publications with AKAP9 and Kidney
 Testis Antibodies  >2 publications with AKAP9 and Testis
 Eye Antibodies  >2 publications with AKAP9 and Eye
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