NP_001070450.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
15,285 Da
NCBI Official Full Name
ubiquitin-like protein ATG12
NCBI Official Synonym Full Names
ATG12 autophagy related 12 homolog (S. cerevisiae)<
NCBI Protein Information
ubiquitin-like protein ATG12; autophagy-related protein 12
UniProt Protein Name
Ubiquitin-like protein ATG12
UniProt Synonym Protein Names
Autophagy-related protein 12; APG12-like
UniProt Synonym Gene Names
UniProt Entry Name
ATG12_BOVIN
UniProt Comments for ATG12
Function: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus
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Pathways associated with ATG12 elisa kit
Diseases associated with ATG12 elisa kit
Organs/Tissues associated with ATG12 elisa kit
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