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ABCA7 elisa kit :: Bovine ATP-binding cassette sub-family A member 7 (ABCA7) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7229686 ABCA7 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit

 Also Known As   

Bovine ATP-binding cassette sub-family A member 7 (ABCA7) ELISA Kit

 Product Gene Name   

ABCA7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605414
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 Species Reactivity    Bovine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ABCA7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ABCA7 purchase    MBS7229686 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATP-binding cassette sub-family A member 7 (ABCA7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ABCA7. The ELISA analytical biochemical technique of the MBS7229686 kit is based on ABCA7 antibody-ABCA7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ABCA7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ABCA7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ABCA7 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for ABCA7. It may not necessarily be applicable to this product.
 NCBI GI #    150417984
 NCBI GeneID    10347
 NCBI Accession #    NP_061985.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_019112.3 [Other Products]
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 UniProt Secondary Accession #    Q96S58; Q9BZC4; Q9NR73; Q9UKP8 [Other Products]
 UniProt Related Accession #    Q8IZY2 [Other Products]
 Molecular Weight    218,497 Da
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 NCBI Official Full Name    ATP-binding cassette sub-family A member 7
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family A (ABC1), member 7
 NCBI Official Symbol    ABCA7 [Similar Products]
 NCBI Official Synonym Symbols   
ABCX; ABCA-SSN
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family A member 7; autoantigen SS-N; macrophage ABC transporter
 UniProt Protein Name    ATP-binding cassette sub-family A member 7
 UniProt Synonym Protein Names   
ABCA-SSN; Autoantigen SS-N; Macrophage ABC transporter
 Protein Family    ABC transporter A family
 UniProt Gene Name    ABCA7 [Similar Products]
 UniProt Entry Name    ABCA7_HUMAN
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 NCBI Summary for ABCA7    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCA7    ABCA7: Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation. Belongs to the ABC transporter superfamily. ABCA family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi membrane; Golgi apparatus; cell surface; apical plasma membrane; cytoplasm; integral to membrane; plasma membrane; endosome membrane; ATP-binding cassette (ABC) transporter complex; phagocytic cup

Molecular Function: apolipoprotein A-I receptor activity; phospholipid transporter activity; transporter activity; ATPase activity; ATP binding

Biological Process: phospholipid efflux; positive regulation of ATPase activity; negative regulation of amyloid precursor protein biosynthetic process; positive regulation of phagocytosis; cholesterol efflux; peptide cross-linking; phospholipid scrambling; negative regulation of ATPase activity; transmembrane transport; phagocytosis; memory
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 Research Articles on ABCA7    1. The minor G allele frequency of the rs1788799 polymorphisms in NPC1 might be a protective factor while the rs3764650 polymorphisms of ABCA7 might not be related to sporadic Alzheimer's disease in the Han Chinese population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ABCA7 elisa kitPathways associated with ABCA7 elisa kit
 Reference Product  PubMed Publications
 MS4A6A elisa kit  >15 publications with ABCA7 and MS4A6A
 ABCA2 elisa kit  >7 publications with ABCA7 and ABCA2
 MS4A4E elisa kit  >6 publications with ABCA7 and MS4A4E
 ABCD4 elisa kit  >4 publications with ABCA7 and ABCD4
 ABCF2 elisa kit  >3 publications with ABCA7 and ABCF2
 ABCB6 elisa kit  >2 publications with ABCA7 and ABCB6
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with ABCA7 elisa kitOrgans/Tissues associated with ABCA7 elisa kit
 Disease Name  Pubmed Publications
 Alzheimer Disease Antibodies  >36 publications with ABCA7 and Alzheimer Disease
 Nervous System Diseases Antibodies  >35 publications with ABCA7 and Nervous System Diseases
 Brain Diseases Antibodies  >33 publications with ABCA7 and Brain Diseases
 Disease Progression Antibodies  >6 publications with ABCA7 and Disease Progression
 Cognition Disorders Antibodies  >3 publications with ABCA7 and Cognition Disorders
 Ovarian Neoplasms Antibodies  >2 publications with ABCA7 and Ovarian Neoplasms
 Inflammation Antibodies  >2 publications with ABCA7 and Inflammation
 Neoplasm Metastasis Antibodies  >1 publications with ABCA7 and Neoplasm Metastasis
 Skin Diseases Antibodies  >1 publications with ABCA7 and Skin Diseases
 Liver Neoplasms Antibodies  >1 publications with ABCA7 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >29 publications with ABCA7 and Brain
 Blood Antibodies  >12 publications with ABCA7 and Blood
 Spleen Antibodies  >5 publications with ABCA7 and Spleen
 Mammary Gland Antibodies  >4 publications with ABCA7 and Mammary Gland
 Ovary Antibodies  >3 publications with ABCA7 and Ovary
 Bone Antibodies  >3 publications with ABCA7 and Bone
 Bone Marrow Antibodies  >3 publications with ABCA7 and Bone Marrow
 Testis Antibodies  >3 publications with ABCA7 and Testis
 Lung Antibodies  >3 publications with ABCA7 and Lung
 Thymus Antibodies  >2 publications with ABCA7 and Thymus
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