NP_037396.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,034 Da
NCBI Official Full Name
ATP-dependent RNA helicase DDX25
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box helicase 25
NCBI Official Synonym Symbols
NCBI Protein Information
ATP-dependent RNA helicase DDX25; DEAD box protein 25; DEAD (Asp-Glu-Ala-Asp) box polypeptide 25; gonadotropin-regulated testicular RNA helicase; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 25
UniProt Protein Name
ATP-dependent RNA helicase DDX25
UniProt Synonym Protein Names
DEAD box protein 25; Gonadotropin-regulated testicular RNA helicase
UniProt Synonym Gene Names
UniProt Entry Name
DDX25_HUMAN
NCBI Summary for DDX25
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein is a gonadotropin-regulated and developmentally expressed testicular RNA helicase. It may serve to maintain testicular functions related to steroidogenesis and spermatogenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for DDX25
DDX25: ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development. Belongs to the DEAD box helicase family. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Helicase; Cell development/differentiation; EC 3.6.4.13
Chromosomal Location of Human Ortholog: 11q24
Cellular Component: cytoplasm; nucleus
Molecular Function: RNA binding; ATP-dependent RNA helicase activity; ATP binding
Biological Process: regulation of translation; mRNA export from nucleus; multicellular organismal development; spermatid development
Research Articles on DDX25
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Products associated with DDX25 elisa kit
Diseases associated with DDX25 elisa kit
Organs/Tissues associated with DDX25 elisa kit
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