View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List ACTalpha1 elisa kit :: Bovine Actin Alpha 1, Skeletal Muscle ELISA Kit Catalog # MBS745905 Unit / Price 48-Strip-Wells / $495 +1 FREE 8GB USB 96-Strip-Wells / $700 +1 FREE 8GB USB 5x96-Strip-Wells / $3,105 +3 FREE 8GB USB 10x96-Strip-Wells / $5,865 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Actin Alpha 1, Skeletal Muscle (ACTalpha1), ELISA Kit Full Product Name Bovine Actin Alpha 1, Skeletal Muscle ELISA Kit Product Gene Name ACTalpha1 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Request for Current Manual Insert Request Current Manual OMIM 255310 Species Reactivity Bovine Samples Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate Preparation and Storage Store all reagents at 2-8 degree C. Sample Preparation We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team ISO Certification Manufactured in an ISO 13485:2016 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of ACTalpha1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for ACTalpha1 purchase MBS745905 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Actin Alpha 1, Skeletal Muscle (ACTalpha1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACTalpha1. The ELISA analytical biochemical technique of the MBS745905 kit is based on ACTalpha1 antibody-ACTalpha1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACTalpha1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACTalpha1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Product Categories/Family for ACTalpha1 elisa kit Signal Transduction NCBI/Uniprot data below describe general gene information for ACTalpha1. It may not necessarily be applicable to this product. NCBI GI # 30908859 NCBI GeneID 58 UniProt Secondary Accession # P02568; P99020; Q5T8M9[Other Products] UniProt Related Accession # P68133[Other Products] Molecular Weight 42,051 Da TOP NCBI Official Full Name actin alpha 1 skeletal muscle protein NCBI Official Synonym Full Names actin, alpha 1, skeletal muscle NCBI Official Symbol ACTA1 [Similar Products] NCBI Official Synonym Symbols ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; CFTD1; CFTDM [Similar Products] NCBI Protein Information actin, alpha skeletal muscle; nemaline myopathy type 3 UniProt Protein Name Actin, alpha skeletal muscle UniProt Synonym Protein Names Alpha-actin-1 UniProt Gene Name ACTA1 [Similar Products] UniProt Synonym Gene Names ACTA [Similar Products] UniProt Entry Name ACTS_HUMAN TOP NCBI Summary for ACTalpha1 The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008] TOP UniProt Comments for ACTalpha1 ACTA1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with TTID. Interacts (via its C-terminus) with USP25; the interaction occurs for all USP25 isoforms but is strongest for isoform USP25m in muscle differentiating cells. Belongs to the actin family.Protein type: Motility/polarity/chemotaxis; Cytoskeletal; Cell development/differentiation; ContractileChromosomal Location of Human Ortholog: 1q42.13Cellular Component: extracellular space; sarcomere; stress fiber; actin filament; cytosol; striated muscle thin filament; actin cytoskeletonMolecular Function: protein binding; myosin binding; structural constituent of cytoskeleton; ADP binding; ATP bindingBiological Process: skeletal muscle fiber adaptation; muscle contraction; response to steroid hormone stimulus; muscle thin filament assembly; response to mechanical stimulus; response to extracellular stimulus; response to lithium ion; skeletal muscle fiber development; cell growth; muscle filament slidingDisease: Nemaline Myopathy 3; Myopathy, Congenital, With Fiber-type Disproportion Research Articles on ACTalpha1 1. The predominant pathway mediated by Australian bat lyssavirus G envelope for internalization into HEK293T cells is clathrin-and actin-dependent also requiring Rab5. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with ACTalpha1 elisa kit Reference Product PubMed Publications TPM3 elisa kit >30 publications with ACTalpha1 and TPM3 ACTC1 elisa kit >2 publications with ACTalpha1 and ACTC1 Pathways associated with ACTalpha1 elisa kit Products by Pathway Pathway Diagram Caspase Cascade In Apoptosis Pathway antibodies Caspase Cascade In Apoptosis Pathway Diagram Hypothetical Network For Drug Addiction Pathway antibodies Hypothetical Network For Drug Addiction Pathway Diagram Myometrial Relaxation And Contraction Pathways antibodies Myometrial Relaxation And Contraction Pathways Diagram RhoA Signaling Pathway antibodies RhoA Signaling Pathway Diagram Signaling Events Mediated By Focal Adhesion Kinase Pathway antibodies Signaling Events Mediated By Focal Adhesion Kinase Pathway Diagram Striated Muscle Contraction Pathway antibodies Striated Muscle Contraction Pathway Diagram Diseases associated with ACTalpha1 elisa kit Disease Name Pubmed Publications Nervous System Diseases Antibodies >84 publications with ACTalpha1 and Nervous System Diseases MYOPATHY, CONGENITAL, WITH FIBER-TYPE DISPROPORTION Antibodies >66 publications with ACTalpha1 and MYOPATHY, CONGENITAL, WITH FIBER-TYPE DISPROPORTION Nemaline myopathy 3 Antibodies >19 publications with ACTalpha1 and Nemaline myopathy 3 Heart Diseases Antibodies >18 publications with ACTalpha1 and Heart Diseases Hypertrophy Antibodies >17 publications with ACTalpha1 and Hypertrophy Cardiovascular Diseases Antibodies >16 publications with ACTalpha1 and Cardiovascular Diseases Disease Models, Animal Antibodies >12 publications with ACTalpha1 and Disease Models, Animal Fibrosis Antibodies >6 publications with ACTalpha1 and Fibrosis Brain Diseases Antibodies >3 publications with ACTalpha1 and Brain Diseases Hepatomegaly Antibodies >2 publications with ACTalpha1 and Hepatomegaly Organs/Tissues associated with ACTalpha1 elisa kit Organ/Tissue Name Pubmed Publications Muscle Antibodies >124 publications with ACTalpha1 and Muscle Heart Antibodies >28 publications with ACTalpha1 and Heart Brain Antibodies >13 publications with ACTalpha1 and Brain Embryonic Tissue Antibodies >6 publications with ACTalpha1 and Embryonic Tissue Nerve Antibodies >5 publications with ACTalpha1 and Nerve Bone Antibodies >5 publications with ACTalpha1 and Bone Lung Antibodies >3 publications with ACTalpha1 and Lung Adipose Tissue Antibodies >2 publications with ACTalpha1 and Adipose Tissue Eye Antibodies >2 publications with ACTalpha1 and Eye Kidney Antibodies >2 publications with ACTalpha1 and Kidney TOP